Results 151 to 160 of about 8,763,296 (354)

Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors [PDF]

, 2017
Victoria Stepanova, К. В. Дергилев, Kelci R. Holman, Yelena Parfyonova, З. И. Цоколаева, Mimi Teter, Elena N. Atochina‐Vasserman, Alla Volgina, С. В. Зайцев, Shane P. Lewis, Fedor Zabozlaev, Kseniya Obraztsova, Vera P. Krymskaya, Douglas B. Cines   +13 more
openalex   +1 more source

Understanding the tumor immune microenvironment (TIME) for effective therapy

Nature Network Boston, 2018
M. Binnewies, Edward W. Roberts, K. Kersten, Vincent Chan, Douglas Fearon, M. Merad, L. Coussens, D. Gabrilovich, Suzanne Ostrand-Rosenberg, Suzanne Ostrand-Rosenberg, C. Hedrick, R. Vonderheide, M. Pittet, R. Jain, W. Zou, T. Howcroft, E. Woodhouse, R. Weinberg, M. Krummel   +18 more
semanticscholar   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Trombin és ischémia együttes hatása a vér-agy-gát sejtjeire = The effects of thrombin and ischemia on the cells of the blood-brain-barrier [PDF]

, 2007
A vér-agy-gát (VAG) sejtjeiben, agyi kapilláris endotél sejtekben és asztrocitákban vizsgáltuk trombin és receptorainak kölcsönhatását.. A trombin szignalizáció meghatározott lépéseit tanulmányoztuk, az intracelluláris Ca szint változását és az ERK ...
Bartha, Katalin, Dömötör, Eszter, Machovich, Raymund, Vajda, Szilvia, Ádám, Veronika   +4 more
core  

A novel NF2 splicing mutant causes neurofibromatosis type 2 via liquid-liquid phase separation with large tumor suppressor and Hippo pathway

, 2022
Zexiao Jia, Shuxu Yang, Mengyao Li, Zhaoying Lei, Xue Ding, Mingjie Fan, Dixian Wang, Dajiang Xie, Hui Zhou, Yue Qiu, Qianqian Zhuang, Dan Li, Wei Yang, Xuchen Qi, Xiaohui Cang, Jingwei Zhao, Wenqi Wang, Aifu Lin, Qingfeng Yan   +18 more
openalex   +1 more source

The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)

IEEE Transactions on Medical Imaging, 2015
Bjoern H Menze, A. Jakab, S. Bauer, Jayashree Kalpathy-Cramer, K. Farahani, J. Kirby, Y. Burren, N. Porz, J. Slotboom, R. Wiest, L. Lanczi, E. Gerstner, M. Weber, T. Arbel, B. Avants, N. Ayache, Patricia Buendia, D. Collins, Nicolas Cordier, Jason J. Corso, A. Criminisi, T. Das, H. Delingette, Çağatay Demiralp, C. Durst, M. Dojat, Senan Doyle, Joana Festa, F. Forbes, Ezequiel Geremia, B. Glocker, P. Golland, Xiaotao Guo, A. Hamamci, K. Iftekharuddin, R. Jena, N. John, E. Konukoglu, D. Lashkari, J. Mariz, Raphael Meier, Sérgio Pereira, Doina Precup, S. Price, Tammy Riklin-Raviv, Syed M. S. Reza, Michael T. Ryan, Duygu Sarikaya, L. Schwartz, Hoo-Chang Shin, J. Shotton, Carlos Alberto Silva, N. Sousa, N. Subbanna, G. Székely, Thomas J. Taylor, O. Thomas, N. Tustison, Gözde B. Ünal, F. Vasseur, M. Wintermark, Dong Hye Ye, Liang Zhao, Binsheng Zhao, Darko Zikic, M. Prastawa, M. Reyes, K. V. Leemput   +67 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Clinicopathological observation and prognostic factors of invasive breast cancer with medullary in Xinjiang

BMC Medical Informatics and Decision Making
Background Invasive breast cancer (BC) with medullary is a special type of BC, accounting for 3 ~ 6% of invasive BC. To investigate clinicopathological characteristics concerning invasive BC with medullary in Xinjiang area and analyze the prognostic ...
Yan Li, Xiaoping Ma, Zhenhui Zhao, Li Li, Chunyan Gao, Dan Liu, Bingyu Li, Bing Zhao   +7 more
doaj   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Autonomic modulation of the immune response and implications for CNS malignancies

npj Precision Oncology
While the central nervous system (CNS) has long been known to regulate global physiologic processes, its role in regulating immune responses has only relatively recently been appreciated.
Lucas P. Wachsmuth, Ethan S. Srinivasan, Bhairavy J. Puviindran, Aden P. Haskell-Mendoza, Tyrone DeSpenza, Peter E. Fecci   +5 more
doaj   +1 more source