Results 281 to 290 of about 6,418,846 (364)

A STUDY OF THE BETA 17 KETO-STEROIDS IN A CASE OF PSEUDOHERMAPHRODITISM DUE TO ADRENAL CORTICAL TUMOR

, 1948
Leon J. Leahy, Winfield L. Butsch
openalex   +2 more sources

A malignant choroid plexus tumor with heterologous differentiation and BAP1 deletion suggesting choroid plexus blastoma. [PDF]

Free Neuropathol
Tauziède-Espariat A, Métais A, Guerrini-Rousseau L, Sassi F, Hasty L, Saffroy R, Dangouloff-Ros V, Beccaria K, Servant E, Varlet P.   +9 more
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Cell-free DNA-based inference of the activities of 370 + transcription factors mirrors their activities in tumors. [PDF]

BMC Genomics
Tamaki R, Sagane K, Li SD, Hoshi T.
europepmc   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression. [PDF]

Mol Biomed
Zhao K, Zhang F, Qin Q, Zhang D, Yang F, Huang Y, Deng R, Jing H, Xiao W, Miao H, Shi R.   +10 more
europepmc   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

A Case of Hypervascular Vestibular Schwannoma with Ventricular Enlargement Improved by the Tumor Volume Reduction Effect of Preoperative Embolization. [PDF]

J Neuroendovasc Ther
Sakamoto H, Hashimoto T, Kikuno M, Okada H, Matsunaga K, Kawamata G, Kohno M.   +6 more
europepmc   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Malignant cutaneous adnexal neoplasms with distant brain metastasis: an aggressive behavior. Illustrative cases. [PDF]

J Neurosurg Case Lessons
Vargas-Urbina J, Martinez-Silva R, Rojas-Panta G, Ponce-Manrique G, Flores-Castillo J, Anicama-Lima W.   +5 more
europepmc   +1 more source