Results 291 to 300 of about 8,293,788 (383)

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

Cell, 2013
Jakob Lovén, Heather A. Hoke, Charles Y. Lin, Ashley Lau, David A. Orlando, C. Vakoc, J. Bradner, Tong Ihn Lee, R. Young   +8 more
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Inhibition of TFF3 improves the infiltration and function of CD8⁺ T cells by downregulating the expression of PD-L1 in colorectal cancer. [PDF]

Int J Colorectal Dis
Pan X, Li J, Zhu J, Wang X, Liu Y, Chen S, Wang P.   +6 more
europepmc   +1 more source

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

Cell, 1997
M. O’Reilly, T. Boehm, Y. Shing, N. Fukai, G. Vasios, William Arbuthnot Sir Lane, E. Flynn, J. Birkhead, B. Olsen, J. Folkman   +9 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Rare Case of Undifferentiated Embryonal Sarcoma of the Liver that Contained an Adenocarcinoma Component. [PDF]

Surg Case Rep
Watanabe A, Enokida Y, Suzuki M, Takada T, Yoshida T, Imaizumi J, Sohda M, Iijima M, Ojima H, Shirabe K.   +9 more
europepmc   +1 more source

Tumor-associated macrophages: from mechanisms to therapy.

Immunity, 2014
R. Noy, J. Pollard
semanticscholar   +1 more source