Results 21 to 30 of about 1,149 (191)
Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads [PDF]
, 2017 Allosteric compounds that stimulate Hsp90 adenosine triphosphatase (ATPase) activity were rationally designed, showing anticancer potencies in the low micromolar to nanomolar range.
Agard, Da +10 more
core +1 more source
Revista Peruana de Ginecología y Obstetricia, 2015 El término tumor de Krukenberg debe reservarse para aquellas metástasis que contiene cantidades importantes de células en anillo de sello con producción intracelular de mucina y reacción sarcomatoide difusa del estroma ovárico. Esta limitación es importante, porque los tumores con estas características microscópicas también tienen características ...
Marissa Limas, David Huaraz
openaire +2 more sources
Tumor de Krukenberg del ovario asociado a teratoma maduro [PDF]
Revista chilena de obstetricia y ginecología, 2015 Se reporta un caso excepcional de tumor de Krukenberg ovárico bilateral asociado a teratoma maduro encontrado en una mujer de 54 años. La ecografía mostró al lado derecho tumor ovárico sólido de 55 mm y al lado izquierdo tumor quístico de 125 mm. Se realizó histerectomía total, salpingooforectomía bilateral, resección del epiplón mayor y muestras ...
Mucientes H, Francisco +6 more
openaire +3 more sources
Robotic total gastrectomy with intracorporeal robot-sewn anastomosis. A novel approach adopting the double-loop reconstruction method [PDF]
, 2015 Gastric cancer constitutes a major health problem. Robotic surgery has been progressively developed in this field. Although the feasibility of robotic procedures has been demonstrated, there are unresolved aspects being debated, including the ...
Cirocchi, Roberto +13 more
core +2 more sources
Krukenberg tumor in a young female arising from a primary adenocarcinoma of stomach: a case report [PDF]
, 2021 Krukenberg tumor is a malignancy of ovary that metastasizes from a primary site. Krukenberg tumors are uncommon and account for less than 2% of all ovarian tumors.
Davda, Mansi +3 more
core +2 more sources
PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression [PDF]
, 2015 To overcome cancer cells resistance to pharmacological therapy, the development of new therapeutic approaches becomes urgent. For this purpose, the use of poly(ADP-ribose) polymerase (PARP) inhibitors in combination with other cytotoxic agents could ...
CAIAFA, Paola +11 more
core +2 more sources
, 2023 Krukenberg tumor is a rare form of metastatic ovarian cancer which accounts for less than 2% of all ovarian tumor. Krukenberg tumor mostly occurs after the age of 40 years and is rarely found in younger age group.
Kushla Pathania +3 more
core +2 more sources
Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy. [PDF]
, 2014 Activating mutations in FLT3 confer poor prognosis for individuals with acute myeloid leukemia (AML). Clinically active investigational FLT3 inhibitors can achieve complete remissions but their utility has been hampered by acquired resistance and ...
He, Bai-Liang +9 more
core +5 more sources
A gastrointestinal stromal tumor (GIST) masquerading as an ovarian mass [PDF]
, 2004 Background Malignant gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors originating in the wall of the gastrointestinal tract. Myogenic gastrointestinal stromal tumor, a distinctive morphologic variant is characterized by an unusually ...
Beneduce Pasquale, Carlomagno Giorgio
core +1 more source
Tumor de Krukenberg: pronóstico y tratamiento
RFS Revista Facultad de Salud, 2010 El tumor de Krukenberg es un tumor mucinoso metastásico de ovario que corresponde 1-2% de la totalidad de tumores de este órgano. Es de mal pronóstico y rápida evolución, hasta en un 40% de los casos no se puede determinar el tumor de origen. Se presenta en este caso, una paciente con diagnóstico de una masa y hemorragia uterina anormal.
Cindy Lorena Beltrán Endo +3 more
openaire +2 more sources