Results 111 to 120 of about 37,102 (217)

Case Report: Prenatal presentation of Masson's tumor: first reported case and review of the literature. [PDF]

Front Pediatr
Tanrıkulu B, Erşen Danyeli A, Özek MM.   +2 more
europepmc   +1 more source

6‐Shogaol Attenuates Doxorubicin‐Induced Cardiac and Skeletal Muscle Atrophy by Inhibiting E3 Ubiquitin Ligases and Necroptosis

Phytotherapy Research, EarlyView.
Doxorubicin induces cardiac and skeletal muscle atrophy by upregulating E3 ubiquitin ligases, inhibiting myogenic regulatory factors, and activating necroptosis. Cardiac atrophy can further exacerbate cardiotoxicity. 6‐Shogaol negatively regulates these processes and attenuates doxorubicin‐induced cardiac and skeletal muscle atrophy.
Xipeng Sun, Yaxian Wang, Quanjun Yang, Bo Xin, Jinlu Huang, Cheng Guo   +5 more
wiley   +1 more source

The tumor suppressor NDRG2 promotes ACC1 proteasomal degradation and inhibits de novo lipogenesis in hepatocellular carcinoma. [PDF]

Mol Biomed
Shi Q, Bai Y, Wang J, Ru M, Zhang K, Guo Y, Bai Z, Shen L.   +7 more
europepmc   +1 more source

Shape‐Memory Collagen/Silk‐Fibroin Scaffold for Dura Sealing and Skull Base Regeneration

Small, EarlyView.
ABSTRACT When a skull base defect occurs, reconstruction is typically performed using a variety of autologous grafts, flaps, or synthetic materials. Failure to achieve appropriate management and closure can lead to serious consequences, such as cerebrospinal fluid (CSF) leakage and subsequent meningitis.
SooJung Chae, Donghyeok Kim, Dongyun Kim, JaeYoon Lee, Sang Duk Hong, GeunHyung Kim   +5 more
wiley   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Targeting DHODH reveals a metabolic vulnerability in AR-positive and AR-negative prostate cancer cells via pyrimidine synthesis and metabolic crosstalk with the TCA and urea cycles. [PDF]

Mol Metab
Labroy M, Paré MO, Berthiaume L, Thomas M, Jobin C, Veilleux A, Pelletier M, Pouliot F, Masson JY, Audet-Walsh É.   +9 more
europepmc   +1 more source

Immune escape mechanisms revealed by multifunctional nanoprobes targeting PD‐L1 in hepatic cancer progression

VIEW, EarlyView.
The ICGB@Apt nanoprobes are designed to specifically recognize immune checkpoint molecules such as PD‐L1, thereby enabling precise monitoring of the progression from liver cirrhosis to HC. By binding to PD‐L1 on tumor cells, ICGB@Apt visualizes immune escape events and tumor metastasis while simultaneously reflecting the dynamic interaction between ...
Yiteng Meng, Liwen Jing, Yeda Chen, Shenggang Zhan, Feng Xiong, Wenbiao Chen   +5 more
wiley   +1 more source

Retinal Vasculopathy With Cerebral Leukoencephalopathy Mimicking a Brain Tumor: A Case Report. [PDF]

Cureus
Villegas Hernández JC, Sánchez Sánchez CE, Sahagún Leyva KK, Lozano Santos BS, Ortiz-Plata A, Monroy-Jaramillo N, Tena Suck ML.   +6 more
europepmc   +1 more source

Nodules in an Infant's Fingers

JEADV Clinical Practice, EarlyView.
Adnan Ahmad, Mariam Alshammari, Alsadat Mosbeh, Abeer Albazali, Kawthar Safar, Fatmah Al‐Sughayer   +5 more
wiley   +1 more source

A Novel Antioxidant Peptide Cath‐Np Derived from Nanorana parkeri Attenuates UVB‐Induced Skin Photodamage in Mice

Integrative Zoology, EarlyView.
Schematic representation of Cath‐Np as an antioxidant suppressing acute skin damage caused by ultraviolet B (UVB) radiation in mice. Cath‐Np inhibits the activation of p53 and mitogen‐activated protein kinase pathways while it activates the Nrf2 pathway by its strong antioxidant effects, and accordingly suppresses the expression of inflammatory factors
Hang Liao, Xiaoxiao Shen, Jinwei Chai, Kai wang, Jiena Wu, Jianxi Yang, Ming Chen, Guoxiang Mo, Xueqing Xu   +8 more
wiley   +1 more source