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Epidermal Growth Factor Receptor (EGFR)-Targeting Peptides and Their Applications in Tumor Imaging Probe Construction: Current Advances and Future Perspectives [PDF]

open access: yesBiology
The epidermal growth factor receptor (EGFR) is a key target for both cancer diagnosis and therapeutic interventions. Assessing EGFR expression before therapy has become routine in clinical practice, yet current methods like biopsy and ...
Lu Huang   +13 more
doaj   +2 more sources

Habitat Analysis in Tumor Imaging: Advancing Precision Medicine Through Radiomic Subregion Segmentation [PDF]

open access: yesCancer Management and Research
Ling Xiao Wu, Ning Ding, Yi Ding Ji, Yi Chi Zhang, Meng Juan Li, Jia Cheng Shen, Hai Tao Hu, Long Jin, Sheng Nan Yin Department of Medical Imaging, Suzhou Ninth People’s Hospital, Wujiang, Suzhou, Jiangsu, People’s Republic of ChinaCorrespondence: Long ...
Wu LX   +8 more
doaj   +2 more sources

Treatment Response Prediction Using Ultrasound-Based Pre-, Post-Early, and Delta Radiomics in Neoadjuvant Chemotherapy in Breast Cancer

open access: yesFrontiers in Oncology, 2022
ObjectiveTo develop and validate a radiomics nomogram based on pre-treatment, early treatment ultrasound (US) radiomics features combined with clinical characteristics for early prediction of response to neoadjuvant chemotherapy (NAC) in breast cancer ...
Min Yang   +7 more
doaj   +1 more source

Radiomics Applications in Head and Neck Tumor Imaging: A Narrative Review

open access: yesCancers, 2023
Simple Summary Head and neck tumors (HNTs) are associated with a high mortality due to their commonly insidious and asymptomatic development. Regarding risk stratification and long-term patient outcome prediction, routine clinical evaluation by ...
M. Tortora   +8 more
semanticscholar   +1 more source

Development of DNA aptamers for visualization of glial brain tumors and detection of circulating tumor cells

open access: yesMolecular Therapy: Nucleic Acids, 2023
Here, we present DNA aptamers capable of specific binding to glial tumor cells in vitro, ex vivo, and in vivo for visualization diagnostics of central nervous system tumors.
Anna S. Kichkailo   +54 more
doaj   +1 more source

Two-Year Event-Free Survival Prediction in DLBCL Patients Based on In Vivo Radiomics and Clinical Parameters

open access: yesFrontiers in Oncology, 2022
PurposeFor the identification of high-risk patients in diffuse large B-cell lymphoma (DLBCL), we investigated the prognostic significance of in vivo radiomics derived from baseline [18F]FDG PET/CT and clinical parameters.MethodsPre-treatment [18F]FDG PET/
Zsombor Ritter   +15 more
doaj   +1 more source

Applications of Nanoparticle-Antibody Conjugates in Immunoassays and Tumor Imaging

open access: yesAAPS Journal, 2021
Modern diagnostic technologies rely on both in vitro and in vivo modalities to provide a complete understanding of the clinical state of a patient. Nanoparticle-antibody conjugates have emerged as promising systems to confer increased sensitivity and ...
X. Lin   +2 more
semanticscholar   +1 more source

How Different Albumin-Binders Drive Probe Distribution of Fluorescent RGD Mimetics

open access: yesFrontiers in Chemistry, 2021
The biodistribution of medical imaging probes depends on the chemical nature of the probe and the preferred metabolization and excretion routes. Especially targeted probes, which have to reach a certain (sub)cellular destination, have to be guided to the
Carsten Höltke   +9 more
doaj   +1 more source

Exploiting a New Approach to Destroy the Barrier of Tumor Microenvironment: Nano-Architecture Delivery Systems

open access: yesMolecules, 2021
Recent findings suggest that tumor microenvironment (TME) plays an important regulatory role in the occurrence, proliferation, and metastasis of tumors.
Yanting Sun   +3 more
doaj   +1 more source

A Mammary Organoid Model to Study Branching Morphogenesis

open access: yesFrontiers in Physiology, 2022
Branching morphogenesis is the process that gives rise to branched structures in several organs, such as the lung, the kidney, and the mammary gland. Although morphologically well described, the exact mechanisms driving branch elongation and bifurcation ...
Marika Caruso   +5 more
doaj   +1 more source

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