Results 21 to 30 of about 10,254,505 (350)

Affinity probes based on small-molecule inhibitors for tumor imaging

open access: yesFrontiers in Oncology, 2022
Methods for molecular imaging of target areas, including optical imaging, radionuclide imaging, magnetic resonance imaging and other imaging technologies, are helpful for the early diagnosis and precise treatment of cancers.
Xinzeyu Yi   +3 more
doaj   +1 more source

Tumor Receptor Imaging [PDF]

open access: yesJournal of Nuclear Medicine, 2008
Tumor receptors play an important role in carcinogenesis and tumor growth and have been some of the earliest targets for tumor-specific therapy, for example, the estrogen receptor in breast cancer. Knowledge of receptor expression is key for therapy directed at tumor receptors and traditionally has been obtained by assay of biopsy material.
David A, Mankoff   +4 more
openaire   +2 more sources

Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

open access: yesTheranostics, 2020
In recent years, much progress has been motivated in stimuli-responsive nanocarriers, which could response to the intrinsic physicochemical and pathological factors in diseased regions to increase the specificity of drug delivery.
P. Mi
semanticscholar   +1 more source

Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases (BTIP-BM).

open access: yesNeuro-Oncology, 2020
A recent meeting was held on March 22, 2019, among the U.S. Food and Drug Administration (FDA), clinical scientists, pharmaceutical and biotech companies, clinical trials cooperative groups, and patient advocacy groups to discuss challenges and potential
T. Kaufmann   +19 more
semanticscholar   +1 more source

“Click-to-Clear”: A Strategy to Minimize Radioactivity from the Blood Pool Utilizing Staudinger Ligation

open access: yesPharmaceutics, 2023
The availability of several bioorthogonal reactions that can proceed selectively and efficiently under physiologically relevant conditions has garnered the interest of biochemists and organic chemists alike. Bioorthogonal cleavage reactions represent the
Nisarg Soni   +9 more
doaj   +1 more source

Noninvasive depth estimation using tissue optical properties and a dual-wavelength fluorescent molecular probe in vivo [PDF]

open access: yes, 2017
Translation of fluorescence imaging using molecularly targeted imaging agents for real-time assessment of surgical margins in the operating room requires a fast and reliable method to predict tumor depth from planar optical imaging.
Achilefu, Samuel   +4 more
core   +2 more sources

Multimodality imaging in vivo for preclinical assessment of tumor-targeted doxorubicin nanoparticles. [PDF]

open access: yes, 2012
This study presents a new multimodal imaging approach that includes high-frequency ultrasound, fluorescence intensity, confocal, and spectral imaging to improve the preclinical evaluation of new therapeutics in vivo.
Chu, David   +7 more
core   +3 more sources

Modification of PEG reduces the immunogenicity of biosynthetic gas vesicles

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Nanobubbles have received great attention in ultrasound molecular imaging due to their capability to pass through the vasculature and reach extravascular tissues.
Yuanyuan Wang   +10 more
doaj   +1 more source

Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]

open access: yes, 2018
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar   +8 more
core   +2 more sources

Preclinical Analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and In Vivo Imaging. [PDF]

open access: yes, 2018
The tumor specificity of JAA-F11, a novel monoclonal antibody specific for the Thomsen-Friedenreich cancer antigen (TF-Ag-alpha linked), has been comprehensively studied by in vitro immunohistochemical (IHC) staining of human tumor and normal tissue ...
Adams, Julia   +13 more
core   +2 more sources

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