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The tumor microenvironment at a glance
Journal of Cell Science, 2012Cancers are not just masses of malignant cells but complex ‘rogue’ organs, to which many other cells are recruited and can be corrupted by the transformed cells. Interactions between malignant and non-transformed cells create the tumor microenvironment (TME).
Melania Capasso +2 more
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The Tumor Microenvironment: Methods and Protocols
Methods in Molecular Biology, 2023I. P. Witz
semanticscholar +1 more source
2006
After more than 30 yr of crusading against cancer, targeting mostly the tumor cell cycle, the need for novel therapeutic strategies has become increasingly clear. Survival and expansion of tumor cells cannot be achieved in the absence of a favorable microenvironment, the main components of which are leukocytes, vascular cells, and fibroblasts.
George Coukos, Jose-Ramon Conejo-Garcia
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After more than 30 yr of crusading against cancer, targeting mostly the tumor cell cycle, the need for novel therapeutic strategies has become increasingly clear. Survival and expansion of tumor cells cannot be achieved in the absence of a favorable microenvironment, the main components of which are leukocytes, vascular cells, and fibroblasts.
George Coukos, Jose-Ramon Conejo-Garcia
openaire +2 more sources
Versican in the Tumor Microenvironment
2020Versican is an extracellular matrix proteoglycan with nonredundant roles in diverse biological and cellular processes, ranging from embryonic development to adult inflammation and cancer. Versican is essential for cardiovascular morphogenesis, neural crest migration, and skeletal development during embryogenesis.
Athanasios Papadas +2 more
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Gastric Tumor Microenvironment
2020A compelling body of evidence has demonstrated that gastric cancer has a very particular tumor microenvironment, a signature very suitable to promote tumor progression and metastasis. Recent investigations have provided new insights into the multiple molecular mechanisms, defined by genetic and epigenetic mechanisms, supporting a very active cross talk
Erik Morales +3 more
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Metabolomics in cancer research and emerging applications in clinical oncology
Ca-A Cancer Journal for Clinicians, 2021Daniel R Schmidt +2 more
exaly
Management of glioblastoma: State of the art and future directions
Ca-A Cancer Journal for Clinicians, 2020Aaron C Tan +2 more
exaly