Results 11 to 20 of about 154,929 (213)

Legionella pneumophila Serotype 1 Pneumonia in Patient Receiving Adalimumab

Emerging Infectious Diseases, 2012
We describe a case of severe pneumonia caused by Legionella pneumophila serotype 1 in a woman receiving the tumor necrosis factor–α antagonist to treat rheumatoid arthritis.
Terry C. Wuerz, Owen Mooney, Yoav Keynan
doaj   +1 more source

Rectal tuberculosis after infliximab therapy despite negative screening for latent tuberculosis in a patient with ulcerative colitis [PDF]

Intestinal Research, 2016
Tumor necrosis factor-α inhibitors are now considered as standard therapy for patients with severe inflammatory bowel disease who do not respond to corticosteroids, but they carry a definite risk of reactivation of tuberculosis.
Jatinderpal Singh, Amarender S Puri, Sanjeev Sachdeva, Puja Sakhuja, Kulandaivelu Arivarasan   +4 more
doaj   +1 more source

Ihmor necrosis factor-a inhibitors and cardiovascular risk in rheumatoid arthritis

Современная ревматология, 2012
The use of tumor necrosis factor-α (TNF-α) inhibitors that selectively block important components of the immunopathogenesis of rheumatoid arthritis (RA) is a highly effective and relatively safe treatment for rheumatoid inflammation and can be considered
Tatiana Valentinovna Popkova, D S Novikova, E L Nasonov   +2 more
doaj   +1 more source

THE USE OF TUMOR NECROSIS FACTOR α INHIBITORS IN PATIENTS WITH WEBER-CHRISTIAN DISEASE

Научно-практическая ревматология, 2014
Weber-Christian disease (WCD), also known as idiopathic lobular panniculitis, is a rare disease belonging to the group of diffuse connective tissue diseases. No therapy for WCD has been developed; empirical treatment is typically used.
Olga Nikolayevna Egorova, B S Belov, S G RadenskaLopovok, O V Pushkova, N M Savushkina, Ya B Khrennikov, E L Nasonov   +6 more
doaj   +1 more source

Pulmonary and Peritoneal Tuberculosis Associated with Tumor Necrosis Factor-Alpha Inhibitor Use: A Case Report and Review of the Literature

Case Reports in Pulmonology, 2012
The association between the use of tumor necrosis factor-α inhibitors and the increased risk of granulomatous infections, especially tuberculosis, has been well documented.
Niharika Tipirneni, Marc O. Siegel
doaj   +1 more source

Early intervention with a small molecule inhibitor for tumor nefosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer’s disease

Journal of Neuroinflammation, 2012
Background Chronic neuroinflammation is an important component of Alzheimer’s disease and could contribute to neuronal dysfunction, injury and loss that lead to disease progression.
Gabbita S, Srivastava Minu K, Eslami Pirooz, Johnson Ming F, Kobritz Naomi K, Tweedie David, Greig Nigel H, Zemlan Frank P, Sharma Sherven P, Harris-White Marni E   +9 more
doaj   +1 more source

Paradoxical Reaction to Golimumab: Tumor Necrosis Factor α Inhibitor Inducing Psoriasis Pustulosa

Case Reports in Dermatology, 2013
Importance: Golimumab is a human monoclonal antibody, used for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Adverse reactions are increasing with this class of medication (tumor necrosis factor α inhibitors).
Marien Siqueira Soto Lopes, Beatriz Moritz Trope, Maria Paula Rua Rochedo Rodriguez, Rachel Lima Grynszpan, Tullia Cuzzi, Marcia Ramos-e-Silva   +5 more
doaj   +1 more source

CD8+ T Cells Specific to Apoptosis-Associated Antigens Predict the Response to Tumor Necrosis Factor Inhibitor Therapy in Rheumatoid Arthritis. [PDF]

PLoS ONE, 2015
CD8+ T cells specific to caspase-cleaved antigens derived from apoptotic T cells (apoptotic epitopes) represent a principal player in chronic immune activation, which is known to amplify immunopathology in various inflammatory diseases.
Alessandra Citro, Rossana Scrivo, Helene Martini, Carmela Martire, Paolo De Marzio, Anna Rita Vestri, John Sidney, Alessandro Sette, Vincenzo Barnaba, Guido Valesini   +9 more
doaj   +1 more source

Perspectives for uveitis treatment in rheumatic diseases

Современная ревматология, 2011
The paper describes current approaches to treating uveitis in rheumatic diseases and theoretical backgrounds for using tumor necrosis factor-α (TNF-α) inhibitors. The data available in the literature suggest that anti-TNF-α therapy is highly effective in
Alla Aleksandrovna Godzenko, Alla Aleksandrovna Godzenko   +1 more
doaj   +1 more source

S-1-propenyl-L-cysteine suppresses lipopolysaccharide-induced expression of matrix metalloproteinase-1 through inhibition of tumor necrosis factor-α converting enzyme-epidermal growth factor receptor axis in human gingival fibroblasts.

PLoS ONE, 2023
Periodontal disease is the most common dental health problem characterized by the destruction of connective tissue and the resorption of alveolar bone resulting from a chronic infection associated with pathogenic bacteria in the gingiva.
Hiroshi Nango, Masahiro Ohtani
doaj   +1 more source