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Correction: Impact of tumor necrosis factor-alpha gene variant in pediatric nephrotic syndrome: a meta-analysis. [PDF]
Sci RepVenkatachalapathy Y +6 more
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Guselkumab Improves Patient-Reported Outcomes Among Participants with Psoriatic Arthritis and Inadequate Response to Tumor Necrosis Factor Inhibitors in the COSMOS Study. [PDF]
Rheumatol TherGossec L +8 more
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Association of Pharmacologic Markers of Anti-Tumor Necrosis Factor-α Activity and Etanercept Effectiveness in Juvenile Idiopathic Arthritis. [PDF]
Pharmacol Res PerspectArain MI +5 more
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Developmental & Comparative Immunology, 2004
Since the discovery of tumor necrosis factor (TNF) and lymphotoxin, many structurally related factors have been elucidated in mammals that are grouped together in the TNF Ligand Superfamily. These factors have profound pleiotropic roles involving inflammation, apoptosis, cell proliferation and stimulation of the immune system.
Frederick W, Goetz +2 more
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Since the discovery of tumor necrosis factor (TNF) and lymphotoxin, many structurally related factors have been elucidated in mammals that are grouped together in the TNF Ligand Superfamily. These factors have profound pleiotropic roles involving inflammation, apoptosis, cell proliferation and stimulation of the immune system.
Frederick W, Goetz +2 more
openaire +2 more sources
Tumor Necrosis Factor and Anti-Tumor Necrosis Factor Therapies
The Journal of Rheumatology Supplement, 2010Tumor necrosis factor (TNF) plays a crucial role in the pathogenesis of immune-mediated inflammatory diseases (IMID). As a result, the inhibition of TNF is an important therapeutic avenue in the treatment of these pathophysiologically diverse disease states.
Edward C, Keystone, Carl F, Ware
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Seminars in Surgical Oncology, 1989
AbstractTumor necrosis factor (TNF) is a well‐described and characterized cytokine which can be elicited in the intact animal by endotoxin. This factor produces necrosis of subcutaneous tumors in the classic model: Meth A sarcoma in the Balb C mouse. It has been shown to be cytostatic or cytotoxic for a variety of human cancer cell lines, as well as to
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AbstractTumor necrosis factor (TNF) is a well‐described and characterized cytokine which can be elicited in the intact animal by endotoxin. This factor produces necrosis of subcutaneous tumors in the classic model: Meth A sarcoma in the Balb C mouse. It has been shown to be cytostatic or cytotoxic for a variety of human cancer cell lines, as well as to
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1997
The observation of a tumor necrosing effect coincident with infection in a patient with a sarcoma of the neck by Coley [1] more than 100 years ago generated much excitement. Pathogenic bacteria and their products (“Coley s toxins”) were thought to comprise a potential means of tumor therapy.
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The observation of a tumor necrosing effect coincident with infection in a patient with a sarcoma of the neck by Coley [1] more than 100 years ago generated much excitement. Pathogenic bacteria and their products (“Coley s toxins”) were thought to comprise a potential means of tumor therapy.
openaire +1 more source
Medizinische Monatsschrift fur Pharmazeuten, 1987
Tumor necrosis factor (TNF) is cytokine derived from macrophage and shows much promise for application in cancer therapy because of its marked antitumor effects and its high specificity to tumors. Recently, the gene encoding human TNF was expressed in E.
D, Aderka, Y, Levo
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Tumor necrosis factor (TNF) is cytokine derived from macrophage and shows much promise for application in cancer therapy because of its marked antitumor effects and its high specificity to tumors. Recently, the gene encoding human TNF was expressed in E.
D, Aderka, Y, Levo
+7 more sources