Results 71 to 80 of about 2,219,836 (309)

A case of ipsilateral three simultaneous renal cell carcinomas with different histologic types

IJU Case Reports, 2023
Introduction Few reports have presented sporadic multifocal renal cell carcinomas of different histologic types occurring simultaneously in a single kidney.
Satoki Tanaka, Yusuke Goto, Ayumi Fujimoto, Takayuki Arai, Hiroaki Sato, Tomokazu Sazuka, Yusuke Imamura, Shinichi Sakamoto, Jun‐Ichiro Ikeda, Tomohiko Ichikawa   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells [PDF]

, 2012
End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed the nephrotoxicity induced by the immunosuppressive agents’ cyclosporine A (CsA ...
Ryan, Michael P., Michael P. Ryan, O'Connell, Séin, Slattery, Craig, Tara McMorrow, Craig Slattery, Séin O'Connell, McMorrow, Tara   +7 more
core   +1 more source

Small renal cell carcinoma accompanied by extensive inferior vena cava tumor thrombus diagnosed by percutaneous transvenous biopsy

IJU Case Reports
Introduction Up to 10% of patients with renal cell carcinoma present with tumor thrombus in the inferior vena cava. We report that a case of small renal cell carcinoma with tumor thrombus extending above the diaphragm for which transvenous biopsy was ...
Hikaru Tsukada, Nozomi Hayakawa, Koichiro Aida, Shinji Wada, Tsuyoshi Morimoto, Masatomo Doi, Hidefumi Mimura, Junki Koike, Eiji Kikuchi   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Renal vein tumor thrombus from metastatic anal gland adenocarcinoma

Urology Case Reports, 2018
A 62-year-old female with a history of anal gland adenocarcinoma presents with metastatic disease to the kidney with renal vein tumor thrombus extending into the inferior vena cava (IVC). Metastatic disease to the kidney with renal vein tumor thrombus is
Ari P. Bernstein, Judy Sarungbam, Victoria Chernyak, Lakshmi Rajdev, Evan Kovac   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Independent Validation of 2010 Tumor-Node-Metastasis Classification for Renal Cell Carcinoma: A Multi-center Study by the Urooncology Association of Turkey Renal Cancer-Study Group [PDF]

, 2017
Objective: The American Joint Committee on Cancer tumor-node-metastasis (TNM) classification has been updated by the 7th edition in 2010. The objective of the study was to evaluate cancer-specific survival (CSS) in patients with renal cell carcinoma (RCC)
Ozen, Haluk, Dirim, Ayhan, Urooncology Association of Turkey Renal Cancer-Study Group, Cavit Can, Yildirim, Asif, Asıf Yıldırım, Can, Cavit, Haluk Özen, Çağatay Göğüs, Ozkan, Tayyar Alp, Akdogan, Bulent, Gogus, Cagatay, Tayyar Alp Özkan, Saadettin Eskiçorapçı, Turkeri, Levent, Eskicorapci, Sadettin, Renal, Urooncology Assoc Turkey, Özgür Yaycıoğlu, Tukeri, Levent, Levent Türkeri, Ayhan Dirim, Bülent Akdoğan, Yaycioglu, Ozgur, Eskicorapci, Saadettin, Urooncology Association of Turkey Renal Cancer Study Group   +24 more
core   +1 more source

Thrombus-like Tumor of Renal Cell Carcinoma Mimicking Transitional Cell Carcinoma of Kidney: A Case Report

Urology Case Reports, 2017
Renal cell carcinoma (RCC) is the most common malignancy of the kidney. It is not commonly form tumor thrombus in the ureter or renal pelvis. A 29-year-old woman presented with asymptomatic gross hematuria. Contrast CT study revealed a tumor suspected to
Dyandra Parikesit, Chaidir A. Mochtar, Budiana Tanurahardja, Sahat Matondang, Rainy Umbas, Agus Rizal Hamid   +5 more
doaj   +1 more source