Results 81 to 90 of about 1,259,950 (219)

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Surgical management of renal cell carcinoma with associated tumor thrombus extending into the inferior vena cava: A 10-year single-center experience

Urology Research and Practice, 2019
Objective: Renal cell carcinoma (RCC) is a tumor that has a tendency of vascular invasion by extending to the inferior vena cava (IVC) after the renal vein. The total resection of the renal tumor and tumor thrombus is considered the optimal treatment. In
Ahmet Ürkmez, Emre Tokuç, Hüseyin Kanberoğlu, Metin İshak Öztürk, Rıdvan Kayar, Ramazan Topaktaş   +5 more
doaj   +1 more source

Deficiency of high‐molecular‐weight von Willebrand factor mitigates thrombo‐complement injury in an LPS‐induced TMA‐like mouse model

VIEW, EarlyView.
Reduction of high‐molecular‐weight von Willebrand factor disrupts the platelet–complement amplification loop, attenuating microvascular thrombosis, complement deposition, endothelial injury, and organ damage in complement‐mediated thrombotic microangiopathy.
Yang Li, Chihao Zhang, Xiaoqian Xu, Sicong Wang, Xiaofan Hu, Junjie Yao, Xi Wu, Difeng Zhu, Qian Liang, Yeling Lu, Yu Liu, Guanqun Xu, Jiakuan Zhou, Qiulan Ding, Wenman Wu, Ya Li, Jing Dai, Xuefeng Wang   +17 more
wiley   +1 more source

Efficacy and safety of neoadjuvant therapy with tislelizumab plus axitinib for nonmetastatic renal cell carcinoma with inferior vena cava tumor thrombus: a retrospective study

Scientific Reports
In renal cell carcinoma (RCC) patients with inferior vena cava (IVC) tumor thrombus, neoadjuvant therapy could alleviate the burden of tumor thrombus, enhance the safety and feasibility of surgical resection, and improve patient prognosis.
Zhongjie Zhao, Zhengsheng Liu, Kaiyan Zhang, Wei Li, Lijian Zhang, Bingliang Jiang, Bin Chen, Jinchun Xing, Xuegang Wang   +8 more
doaj   +1 more source

Liver metastasis originating from colorectal cancer with macroscopic portal vein tumor thrombosis: a case report and review of the literature

Journal of Medical Case Reports, 2010
Introduction Macroscopic tumor thrombi occupying the main portal branch are rarely seen in patients with liver metastasis. Case presentation A 55-year-old Japanese man who had previously undergone surgery for adenocarcinoma of the ascending colon ...
Tomimaru Yoshito, Sasaki Yo, Yamada Terumasa, Gotoh Kunihito, Noura Shingo, Eguchi Hidetoshi, Miyashiro Isao, Ohue Masayuki, Ohigashi Hiroaki, Yano Masahiko, Ishikawa Osamu, Imaoka Shingi   +11 more
doaj   +1 more source

Clinical Features and Outcomes of Chronic Otitis Media Complications: A 20‐Year Retrospective Study at a Tertiary Hospital

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic otitis media (COM) is a major public health concern, particularly in developing countries. Although complications have decreased with modern antibiotics, they still cause significant morbidity and mortality. This study analyzed the clinical features, bacteriological profiles, and treatment outcomes of COM complications at a ...
Viraporn Atchariyasathian, Nipit Tangchitnob   +1 more
wiley   +1 more source

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao, Shen Zhan, Gang Fu, Shanshan Guo, Lifang Liu, Wei Liu, Guanghui Xiao, Yuzhu Wang, Lihong Zhang   +8 more
wiley   +1 more source

Cine magnetic resonance imaging predicts thrombus adhesion in metastatic renal cell carcinoma with an inferior vena cava tumor thrombus: A case of pathological complete response with pembrolizumab plus lenvatinib

IJU Case Reports
Introduction Renal cell carcinoma with an inferior vena cava tumor thrombus is a challenging disease that requires a multimodal treatment approach. Pembrolizumab plus lenvatinib has displayed promising efficacy in metastatic renal cell carcinoma.
Takuto Hara, Junya Furukawa, Takahiro Tsutiya, Takayuki Kodama, Keiichiro Uehara, Tomoaki Terakawa, Kenichi Harada, Jun Teishima, Yuzo Nakano, Masato Fujisawa   +9 more
doaj   +1 more source

Robot-assisted laparoscopic retroperitoneal lymph node dissection with concomitant inferior vena cava thrombectomy for metastatic mixed testicular germ cell cancer: a case report

Journal of Medical Case Reports, 2019
Background The robot-assisted laparoscopic management of post-chemotherapy retroperitoneal metastasis and inferior vena cava tumor thrombus secondary to testicular cancer is a challenging task for urologists.
Kai Zhang, Gang Zhu, Xingshuai Liu, Jiangke Tian, Yanfei Gu, Mengyao Zhai, Lu Yang, Wei Liu, Hongbo Li, Francisco J. Martinez Portillo   +9 more
doaj   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source