Results 101 to 110 of about 147,443 (317)

Liver resection for metastatic colorectal cancer [PDF]

open access: yes, 1986
From 1975 to 1985, 60 patients with isolated hepatic metastases from colorectal cancer were treated by 17 right trisegmentectomies, five left trisegmentectomies, 20 right lobectomies, seven left lobectomies, eight left lateral segmentectomies, and three ...
Esquivel, CO   +3 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Resistencia Concomitante Antitumoral: un posible mecanismo de control de las metástasis [PDF]

open access: yes, 2017
En mayo de 1978, cuando ingresé en la Sección Leucemia Experimental de la Academia Nacional de Medicina de Buenos Aires, ciertamente no imaginé que, 39 años después, iba a estar en este mismo sitio trabajando y escribiendo este artículo. Para algunos,
Ruggiero, Raul Alejandro
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Tumores del tracto urinario [PDF]

open access: yes, 1988
Se revisa un total de 12 tumores del tracto urinario, diagnosticados en un periodo de 8 años. Se expone el diagnóstico, tratamiento y seguimiento de los casos que no fueron sacrificados.The author shows a total number of twelve urinary tract tumors ...
Durall Rivas, Ignacio
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Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

De enfermidade sistêmica à enfermidade local

open access: yesKhronos, 2023
Este artigo apresenta uma análise da obra Sur la Nature et la Guerison des Cancers (1701), do médico francês Claude Gendron, publicada em Paris. O ponto de atenção deposita-se em sua análise sobre a gênese tumoral, que se distancia parcialmente do ...
Bernardo Ternus de Abreu   +2 more
doaj  

Hallazgos tomográficos y diagnóstico histológico en pacientes con tumores rinossinusales atendidos en el servicio de ORL del Hospital Escuela Antonio Lenin Fonseca Martínez de Septiembre 2013 a Octubre 2014 [PDF]

open access: yes, 2014
El presente trabajo se realizó en el Hospital Antonio Lenin Fonseca Durante el periodo de septiembre 2013 a octubre 2014. Se trata de un estudio descriptivo de morbi-mortalidad para conocer los hallazgos radiológicos y determinar la concordancia con el ...
Guardado Machado, Raúl Francisco
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Prevención y atención de las necesidades educativas especiales de los niños con tumores intracraneales [PDF]

open access: yes, 2000
Se describen las necesidades educativas especiales de los niños con tumores intracraneales en función e la localización y naturaleza del tumor y de los ...
Grau Rubio, Claudia
core  

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