Results 161 to 170 of about 4,011,391 (378)
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Revisión sistemática de los tumores cerebrales y los síntomas comunicativos [PDF]
Introducción: Esta revisión bibliográfica parte de diversas descripciones de casos de pacientes con tumores cerebrales, recogidas en 17 artículos.
Pastor Tejedor, Sara
core
Oropharyngeal cancer: an emergent disease?
Oropharyngeal cancer incidence has recently increased, thereby attracting public attention. Akin to other malignancies of the upper aerodigestive tract, it has been attributed to the carcinogenic effects of tobacco and alcohol use.
Martín Granados-García
doaj
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Relação entre o papiloma vírus humano e tumores da cabeça e pescoço [PDF]
Trabalho final de mestrado integrado em em Medicina, área cientifica de Oncologia Médica, apresentado à Faculdade de Medicina da Universidade de CoimbraIntrodução O Papiloma Vírus Humano (HPV) desempenha um papel ainda desconhecido nalguns tumores da ...
Correia, Dora Gabriela Antunes
core
Chromosome studies on some human tumors and tissues of normal origin, grown in vivo and in vitro at the Sloan-Kettering Institute [PDF]
ALBERT LEVAN
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Studies by the barany rotation and caloric tests of tumors of the nervus acusticus [PDF]
Harris H. Vail
openalex +1 more source