Results 161 to 170 of about 8,958 (267)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

ADN tumoral circulante en pacientes con cáncer: perspectivas desde el laboratorio clínico. [PDF]

Adv Lab Med
Illana FJ, Fernández-Galán E, Muñoz-Bravo JL, Amado LV, García Martín C, González-Fernández C, Miró-Cañís S, Trapé J, Martínez-Peinado A, Filella X, González A, Barco Sánchez A, Díaz-Lagares A, en nombre de la Comisión de Marcadores Biológicos del Cáncer de la Sociedad Española de Medicina de Laboratorio.   +13 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

[Prevalence of Esophageal Squamous Cell Carcinoma among Patients with Head and Neck Cancer: A Single-Center Study]. [PDF]

Acta Gastroenterol Latinoam
Martins Lima AV, Carvalho Franco F, Quevedo Penaloza CS, Cadena Aguirre D, Sartori Balbinot R, Rie Imada R, Marioni F, Nobre Moura R, Andrade de Paulo G, Vaz Safatle-Ribeiro A, Menezes da Cunha L, Gonçalves Ferreira F.   +11 more
europepmc   +1 more source

TESTICULAR TUMORS

, 2006
openaire   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

[Brown tumor due to hyperparathyroidism secondary to chronic kidney disease: A clinical case]. [PDF]

Rev Med Inst Mex Seguro Soc
Contreras-Vargas LM, Sánchez-Cuevas M, Haro-Sandoval Y, Paque-Bautista C, González AP, Reyes-Sosa AM, Flores-Rodríguez R, Murguía-Pérez M, Guisao-Valencia CA, Sosa-Bustamante GP.   +9 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

[Primary testicular lymphoma with extranodal involvement in the stomach. Case report]. [PDF]

Rev Med Inst Mex Seguro Soc
Díaz-Fuentes H.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source