Results 201 to 210 of about 1,039,582 (299)

TESTICULAR TUMORS

, 2006
openaire   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction–associated steatohepatitis

Junyan Lyu, Hikari Okada, Hajime Sunagozaka, Kazunori Kawaguchi, Tetsuro Shimakami, Kouki Nio, Kazuhisa Murai, Takayoshi Shirasaki, Mika Yoshida, Kuniaki Arai, Tatsuya Yamashita, Takuji Tanaka, Kenichi Harada, Toshinari Takamura, Shuichi Kaneko, Taro Yamashita, Masao Honda   +16 more
openalex   +1 more source

[Incidence of COVID-19 in cancer patients from the HIGA Alende, Mar del Plata, Argentina, 2020-2021] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Bienaime S, Ballejo C, Ricardo T, Irassar JI, Amezqueta G, Sabuda R, Casatti A, Laspada M, Rodriguez L, Alvarez MA, Dana Smith R.   +10 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The controversial role of CD151 in different solid tumors: promoter or suppressor? [PDF]

Xueqin Gao, Sa Liu, Yubo Cao, Lei Shi, Yuanqin Yin   +4 more
openalex   +1 more source

Intrahepatic Cholangiocarcinoma in Wilson's Disease: 2 Case Reports. [PDF]

GE Port J Gastroenterol
Aguiar JR, Miranda HP, Pereira C.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Antitumor activity of gilteritinib, an inhibitor of AXL, in human solid tumors [PDF]

Zuxiong Zhang, Ruxia Hu, Jie Liu, Xiaohan Yang, Youban Xiao, Xi Xu, Xinxin Liu, Wen Zeng, Shuyong Zhang, Liefeng Wang   +9 more
openalex   +1 more source

[Left atrial myxoma, another cause of mitral stenosis]. [PDF]

Arch Cardiol Mex
Pineda-Guevara SH, Alas-Pineda CU, Alvarado-Guevara CR, Rojas-Gonzáles BJ, Murillo-Córdova AF.   +4 more
europepmc   +1 more source