Results 41 to 50 of about 147,443 (317)

Identification of prognostic factors for survival in patients with metastatic gastric adenocarcinoma in a Mexican population

open access: yesRevista de Gastroenterología de México (English Edition)
Introduction and aims: Gastric adenocarcinoma is among the high-ranking tumors, with respect to frequency and mortality, worldwide. The inflammatory process and immune system activity are associated with oncologic control. Our aim was to identify whether
A.M. León   +8 more
doaj   +1 more source

Oligodendroglioma anaplásico en el nervio óptico de un perro [PDF]

open access: yes, 2013
Los gliomas son tumores no neuronales del tejido nervioso. En el Sistema Nervioso Central (SNC) dependiendo de su origen se clasifican en astrocitomas, oligodendrogliomas, tumores mixtos (oligoastrocitomas), ependimomas y papilomas de plexos coroideos ...
Fernández, F   +3 more
core  

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Suicide gene therapy targeting ewing sarcoma via an ewing-specific GGAA promoter

open access: yesScientific Reports
We recently demonstrated that GGAA promoters (GGAAprom) can be used to drive the expression of therapeutic genes (i.e., Cas9) in vitro and in vivo in a highly specific way in Ewing sarcoma cells.
Saint T. Cervera   +4 more
doaj   +1 more source

Frecuencia de tumores de origen Odontogénico en los maxilares en pacientes atendidos en el Hospital Escuela Dr. Roberto Calderón Gutiérrez en el período comprendido de Enero de 2006 a Octubre de 2009 [PDF]

open access: yes, 2010
Este es un estudio descriptivo de corte transversal realizado en el Hospital Escuela Dr. Roberto Calderón Gutiérrez, en el periodo comprendido del año 2006 a 2009, estudiándose la frecuencia de los tumores de origen odontogénico en las clínicas de ...
González Chavarría, Gabrie
core  

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Identificación de factores pronósticos para supervivencia en pacientes con adenocarcinoma gástrico metastásico en la población mexicana

open access: yesRevista de Gastroenterología de México
Resumen: Introducción y objetivos: El adenocarcinoma gástrico se ubica entre las neoplasias malignas con mayor frecuencia y mortalidad en el mundo. Se ha observado que el proceso inflamatorio y la actividad del sistema inmunológico están asociados al ...
A.M. León   +8 more
doaj   +1 more source

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