Differential Proliferation Effect of the Newly Synthesized Valine, Tyrosine and Tryptophan–Naphthoquinones in Immortal and Tumorigenic Cervical Cell Lines [PDF]
, 2020 Sergio Córdova-Rivas +9 more
openalex +1 more source
KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not? [PDF]
, 2021 Hannu Koistinen +2 more
openalex +1 more source
Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. [PDF]
, 2013 The phosphoinositide 3-kinase (PI3K) signaling cascade is a key mediator of cellular growth, survival and metabolism and is frequently subverted in human cancer.
Bentires-Alj, M +8 more
core +2 more sources
Advanced Materials, EarlyView.We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam +5 more
wiley +1 more source
Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin
OncoTarget, 2016 Developmental transcription programs are epigenetically regulated by the competing actions of polycomb and trithorax (TrxG) protein complexes, which repress and activate genes, respectively.
Laurie K. Svoboda +12 more
semanticscholar +1 more source
Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells. [PDF]
, 2017 Renal cell carcinoma (RCC) is a deadly malignancy due to its tendency to metastasize and resistance to chemotherapy. Stem-like tumor cells often confer these aggressive behaviors.
Dai, Jin +10 more
core +3 more sources
4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa +4 more
wiley +1 more source
Characteristics of Stem Cells from Human Neuroblastoma Cell Lines and in Tumors
Neoplasia: An International Journal for Oncology Research, 2004 Cellular heterogeneity is a hallmark of human neuroblastoma tumors and cell lines. Within a single neuroblastoma are cells from distinct neural crest lineages whose relative abundance is significant for prognosis.
Jeanette D. Walton +7 more
doaj +1 more source
The role of Micro-RNAs in Hepatocellular Carcinoma: From Molecular Biology to Treatment [PDF]
, 2014 Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third leading cause of cancer deaths. microRNAs (miRNAs) are evolutionary conserved small non-coding RNA that negatively regulate gene expression and protein translation ...
Bianconi Maristella +7 more
core +1 more source