Results 181 to 190 of about 66,124 (248)

[Retracted] Inhibition of EMMPRIN by microRNA-124 suppresses the growth, invasion and tumorigenicity of gliomas. [PDF]

Exp Ther Med
Song Y, Bai L, Yan F, Chen C.
europepmc   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

Author Correction: CREB5 promotes tumorigenicity and upregulates druggable cell surface modalities in basal-like breast cancer. [PDF]

NPJ Precis Oncol
Makovec A, Boytim E, Gustafson A, Ludwig M, Wang L, Ali A, Ishani K, Luo C, Bergom HE, John E, Tape S, Kellen S, Deacon A, Dewji FI, Richter C, Cookle L, Moline D, Rennhack JP, Drake JM, Antonarakis ES, Largaespada DA, Ostrander JH, Hwang J.   +22 more
europepmc   +1 more source

Precision medicine based on tumorigenic signaling pathways for triple‑negative breast cancer (Review)

, 2018
Nan Wu, Jinghua Zhang, Jing Zhao, Kun Mu, Jun Zhang, Jin Zhao, Jinpu Yu, Juntian Liu   +7 more
openalex   +2 more sources

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

Advanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu, Zhuoyi Huang, Jintao Li, Yue Li, Zhou Fang, Yiwen Jiang, Keke Wu, Jinshan Guo   +7 more
wiley   +1 more source

Efficacy and safety of intrathecal human umbilical cord-derived mesenchymal stromal cell therapy for bone cancer pain: a preclinical study. [PDF]

Stem Cell Res Ther
Zhang J, Li Y, Ren P, Jiang M, Wu P, Wen Q.   +5 more
europepmc   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Involvement of the FGF8/FGF Receptor Signaling Pathway in the Maintenance and Progression of Fusion-Positive Rhabdomyosarcoma. [PDF]

Mol Cancer Ther
Boudjadi S, Kim H, Chatterjee B, Raut PK, Nguyen TH, Pandey PR, Ur Rasool R, Sun W, Barr FG.   +8 more
europepmc   +1 more source

Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis

, 2018
Lan Li, Yu Cao, Hourong Zhou, Yu Li, Bing He, Xia Zhou, Nie Zhao, Liang Li, Ying Liu, Limin Ye   +9 more
openalex   +2 more sources

PRELID1 and VDAC3 Coordinate a Senescence‐Like State in Germinal Center B Cells to Promote IL‐7–Driven Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
Colorectal cancer is characterized by an immunosuppressive microenvironment that limits immunotherapy efficacy. We identify a senescence‐like state in germinal center B cells driven by the PRELID1–VDAC3 axis, which promotes IL‐7 secretion, alleviates CD8+ T‐cell exhaustion, and enhances antitumor immunity. Targeting this pathway improves responsiveness
Yuhan Liao, Huimeng Xu, Xinghua Zhuo, Shupeng Hu, Lanhui Huang, Zhe Hao, Jianxiong Chen, Yulu Wang, Jun Zhou   +8 more
wiley   +1 more source