Results 191 to 200 of about 66,124 (248)

Autophagy inhibition in LGALS9-overexpressing nasopharyngeal carcinoma unleashes immune response. [PDF]

Autophagy
Pascual C, Klionsky DJ, Klionsky DJ.
europepmc   +1 more source

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

Advanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia, Jinguan Lin, Xianjie Jiang, Linda Oyang, Shiming Tan, Zongyao Ren, Qiu Peng, Qianjin Liao, Yujuan Zhou   +8 more
wiley   +1 more source

Predictive value of circulating cardiomyocyte-specific cell-free DNA levels for heart failure risk after acute ST-segment elevation myocardial infarction. [PDF]

Postepy Kardiol Interwencyjnej
Feng Y, Zhuo Y, Cheng H.
europepmc   +1 more source

Agrobacterium vitis strains lack tumorigenic ability on in vitro grown grapevine stem segments

, 2015
E. Szegedi, Tamás Deák, István Forgács, A. Zok, Róbert Oláh   +4 more
openalex   +2 more sources

CircRSU1 Activates the hnRNPA1/HIF‐1α/CD24 Signaling Axis, Promoting Stemness Features of Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study reveals circRSU1 with important oncogenic roles in hepatocellular carcinoma (HCC). CircRSU1, highly abundant in HCC, interacts with and stabilizes hnRNPA1 from ubiquitination and degradation. This stabilization facilitates hnRNPA1 binding to the internal ribosome entry site of HIF1A to increase HIF‐1α protein translation.
Shuting Xue, Danduo Wei, Yongzhi Zhao, Jinchang Pan, Hanyuan Zhang, Niya Liu, Jianjuan Zhang, Jiaxin Liu, Jianping Jin, Mu Xiao, Xinhua Feng, Aifu Lin, Lei Zhao, Stephanie Roessler, Junfang Ji   +14 more
wiley   +1 more source

Extruded nanovesicles derived from umbilical cord mesenchymal stem cells exhibit No tumorigenic potential. [PDF]

Bioact Mater
Wang F, Li L, Deng J, Mo S, Ai J, Xiao Y, Li Q, Ding D, Zhang Y, Zhou D, Li Z.   +10 more
europepmc   +1 more source

CMTM7 knockdown increases tumorigenicity of human non-small cell lung cancer cells and EGFR-AKT signaling by reducing Rab5 activation

, 2015
Baocai Liu, Yu Su, Ting Li, Wanqiong Yuan, Xiaoning Mo, Henan Li, Qihua He, Dalong Ma, Wenling Han   +8 more
openalex   +2 more sources

Metal‐Supramolecular Drug Delivery System Empowered Meningeal Lymphatic Vessels‐Bridged Intracranial‐Peripheral Dual Immune Modulation for Reversing Glioblastoma Immune Suppression

Advanced Science, EarlyView.
A novel metal‐supramolecular nanoplatform (FLM@VC) enables efficient brain delivery via meningeal lymphatic vessels (MLVs), bypassing the blood‐brain barrier (BBB) through subcutaneous administration. It reprograms tumor‐associated macrophages (TAMs) and remodels the MLVs to promote DC trafficking and CD8+ T cell activation.
Chenxi Zhang, Zhongsheng Xu, Xiaowen Xu, Zening Zhang, Ranran Luo, Pengchen Ren, Yingying Luo, Qiuchi Wu, Xinyu Liu, Guodong Liu, Xiaojing He, Yun Liu   +11 more
wiley   +1 more source

sST2 as a Promising Cardiac Biomarker After Ischemic Stroke With Elevated Systolic Blood Pressure. [PDF]

JACC Asia
Tu Y, Wang M, Wu S, Jiang H, Long J, Peng Y, Zhang Y, Xu T, Xiao G, Zhong C.   +9 more
europepmc   +1 more source

MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression

, 2016
Bin Wang, Jie Yang, Bin Xiao
openalex   +2 more sources