Results 1 to 10 of about 6,476,532 (388)

Extraskeletal Ewing’s sarcoma of the mediastinum: Case report

Frontiers in Oncology, 2023
BackgroundEwing sarcoma (ES) represents the second most common malignant bone tumor in children and young adults. ES is not a frequent finding in sites different from the skeletal.
Aldo Caltavituro, Roberto Buonaiuto, Fabio Salomone, Rocco Morra, Erica Pietroluongo, Pietro De Placido, Marianna Tortora, Annarita Peddio, Fernanda Picozzi, Margaret Ottaviano, Mirella Marino, Sabino De Placido, Sabino De Placido, Giovannella Palmieri, Mario Giuliano, Mario Giuliano   +15 more
doaj   +1 more source

Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response

mBio, 2023
The Epstein-Barr virus (EBV) efficiently transforms primary B cells. Here, we show that this process starts immediately after cellular exposure to infectious viral particles.
Francesco Baccianti, Charlène Masson, Susanne Delecluse, Zhe Li, Remy Poirey, Henri-Jacques Delecluse   +5 more
doaj   +1 more source

Case report: Using DNA short tandem repeats to confirm nongestational origin of pulmonary choriocarcinoma

Frontiers in Oncology, 2022
Gestational trophoblastic neoplasias (GTN) are malignant neoplasms that occur in pregnant or recently pregnant women. Choriocarcinoma (CCA) is a highly aggressive and rare GTN, and cases outside the female genital tract are commonly seen as secondary ...
Filipa Ferreira da Silva, Rita Barata, Inês Rolim, Catarina Carvalheiro, Nuno Gil, Marcos Pantarotto   +5 more
doaj   +1 more source

Does epidural analgesia modify the risk of complications after gastrectomy?

Nowotwory, 2021
INTRODUCTION: The surgical treatment of Gastric Cancer is associated with overall complication rates as high as 50%. The intent of this study was to assess the impact of epidural analgesia (EA) on postoperative complication rates among patients ...
Tomasz Olesiński, Marta Urbańska, Anna Borkowska, Paulina Wieszczy, Dariusz Król, Dorota Rucz, Małgorzata Symonides   +6 more
doaj   +1 more source

Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma

Disease Models & Mechanisms, 2022
There is a paucity of adequate mouse models and cell lines available to study lung squamous cell carcinoma (LUSC). We have generated and characterized two models of phenotypically different transplantable LUSC cell lines, i.e.
Karmele Valencia, Cristina Sainz, Cristina Bértolo, Gabriel de Biurrun, Jackeline Agorreta, Arantza Azpilikueta, Marta Larrayoz, Graziella Bosco, Carolina Zandueta, Miriam Redrado, Esther Redín, Francisco Exposito, Diego Serrano, Mirari Echepare, Daniel Ajona, Ignacio Melero, Ruben Pio, Roman Thomas, Alfonso Calvo, Luis M. Montuenga   +19 more
doaj   +1 more source

The roles of extracellular vesicles in the development, microenvironment, anticancer drug resistance, and therapy of head and neck squamous cell carcinoma

Journal of Experimental & Clinical Cancer Research, 2021
Head and neck squamous cell carcinoma (HNSCC) is one of the main malignant tumours affecting human health, mainly due to delayed diagnosis and high invasiveness.
Xueying Wang, Junnan Guo, Pingyang Yu, Lunhua Guo, Xionghui Mao, Junrong Wang, Susheng Miao, Ji Sun   +7 more
doaj   +1 more source

Evaluation of the incidence of splenic hilar lymph node metastasis in patients operated on for esophagogastric junction cancer

Nowotwory, 2023
INTRODUCTION: The purpose of this study is to evaluate the effect of esophagogastric junction cancer (EGJC) staging on the risk of splenic hilar lymph node involvement. MATERIAL AND METHODS: 312 patients with EGJC after R0 surgery were analyzed; 118 (38%)
Tomasz Olesiński, Marek Szpakowski, Wojciech Każmierczak, Urszula Sulkowska, Andrzej Rutkowski   +4 more
doaj   +1 more source

Episcleral brachytherapy as an effective alternative in vasoproliferative tumors [PDF]

International Journal of Ophthalmology, 2018
The aim of this study is to assess the results of episcleral brachytherapy as treatment of retinal vasoproliferative tumors (RVTs) in a referral Intraocular Tumors Unit (ITU). A retrospective review of all patients diagnosed with vasoproliferative tumors
Marta Para Prieto, Maria Antonia Saornil, Jesús María de Frutos Baraja, Ciro García Álvarez, Patricia Diezhandino García, Francisco López Lara   +5 more
doaj   +1 more source

Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

Nature Communications, 2020
Immune checkpoint inhibitors have limited efficacy in tumors with lower mutational burden and non-permissive microenvironment. Here, the authors show that combining MEK inhibition with an agonist anti-CD40 immunostimulatory antibody improves antitumor ...
Daniel Baumann, Tanja Hägele, Julian Mochayedi, Jennifer Drebant, Caroline Vent, Sven Blobner, Julia Han Noll, Irena Nickel, Corinna Schumacher, Sophie Luise Boos, Aline Sophie Daniel, Susann Wendler, Michael Volkmar, Oliver Strobel, Rienk Offringa   +14 more
doaj   +1 more source

Management of Intracranial Metastases in EGFR-Mutated NSCLC: A Review of Literature following an Unusual Case Report

Case Reports in Oncological Medicine, 2021
The arrival of subsequent generations of tyrosine-kinase inhibitors (TKIs) has significantly broaden the EGFR-mutated lung cancer therapeutic landscape.
Víctor Albarrán, Javier Pozas, Juan José Soto, Jorge Esteban, Elena Corral, Yolanda Lage, Pablo Gajate, Pilar Garrido   +7 more
doaj   +1 more source