Results 1 to 10 of about 1,972,930 (221)

Extraskeletal Ewing’s sarcoma of the mediastinum: Case report

open access: yesFrontiers in Oncology, 2023
BackgroundEwing sarcoma (ES) represents the second most common malignant bone tumor in children and young adults. ES is not a frequent finding in sites different from the skeletal.
Aldo Caltavituro   +15 more
doaj   +1 more source

Tumor Hypoxia and Circulating Tumor Cells [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
openaire   +5 more sources

The Role of ARID1A in Tumors: Tumor Initiation or Tumor Suppression? [PDF]

open access: yesFrontiers in Oncology, 2021
Genes encoding subunits of SWItch/Sucrose Non-Fermenting (SWI/SNF) chromatin remodeling complexes are collectively mutated in 20% of all human cancers, among which the AT-rich interacting domain−containing protein 1A (ARID1A, also known as BAF250a, B120, C1orf4, Osa1) that encodes protein ARID1A is the most frequently mutated, and mutations in ARID1A ...
Shouying Xu, Chao Tang
openaire   +3 more sources

Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response

open access: yesmBio, 2023
The Epstein-Barr virus (EBV) efficiently transforms primary B cells. Here, we show that this process starts immediately after cellular exposure to infectious viral particles.
Francesco Baccianti   +5 more
doaj   +1 more source

Case report: Using DNA short tandem repeats to confirm nongestational origin of pulmonary choriocarcinoma

open access: yesFrontiers in Oncology, 2022
Gestational trophoblastic neoplasias (GTN) are malignant neoplasms that occur in pregnant or recently pregnant women. Choriocarcinoma (CCA) is a highly aggressive and rare GTN, and cases outside the female genital tract are commonly seen as secondary ...
Filipa Ferreira da Silva   +5 more
doaj   +1 more source

Investigation of the invasion front in heterogeneous environments to study the geometry of tumor border [PDF]

open access: yesIranian Journal of Physics Research, 2020
We develop a model to study how invasion front depends on the relevant properties of a cellular environment. To do so, we use a nonlinear reaction-diffusion equation, the Fisher equation, to model the population dynamics.
Y Azimzade, A A Saberi
doaj   +1 more source

The roles of extracellular vesicles in the development, microenvironment, anticancer drug resistance, and therapy of head and neck squamous cell carcinoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2021
Head and neck squamous cell carcinoma (HNSCC) is one of the main malignant tumours affecting human health, mainly due to delayed diagnosis and high invasiveness.
Xueying Wang   +7 more
doaj   +1 more source

Episcleral brachytherapy as an effective alternative in vasoproliferative tumors [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
The aim of this study is to assess the results of episcleral brachytherapy as treatment of retinal vasoproliferative tumors (RVTs) in a referral Intraocular Tumors Unit (ITU). A retrospective review of all patients diagnosed with vasoproliferative tumors
Marta Para Prieto   +5 more
doaj   +1 more source

Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

open access: yesNature Communications, 2020
Immune checkpoint inhibitors have limited efficacy in tumors with lower mutational burden and non-permissive microenvironment. Here, the authors show that combining MEK inhibition with an agonist anti-CD40 immunostimulatory antibody improves antitumor ...
Daniel Baumann   +14 more
doaj   +1 more source

MR imaging for evaluation of lesions of the cranial vault: a pictorial essay [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2003
PURPOSE: A variety of diseases affect the calvaria. They may be identified clinically as palpable masses or incidentally in radiologic examinations. There are many diagnostic possibilities, including congenital, neoplastic, inflammatory and traumatic ...
Lázaro Amaral   +5 more
doaj   +1 more source

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