Results 1 to 10 of about 2,065,105 (317)

Somatic copy number alterations profiling in non-small cell lung cancer and their correlation with clinical efficacy in first-line treatment

Genome Medicine
Background Immune checkpoint inhibitors (ICI) are the current standard-of-care first-line treatment for advanced non-small cell lung cancer (NSCLC) without actionable genomic alterations.
Ilaria Priano, Ramon Amat, Caterina Carbonell, Aina Arbusà-Roca, Patricia Iranzo, Nuria Pardo, Mireia Soleda, Gerard Romero-Sola, Barbara Sinigaglia, Sara Polo-Alonso, Ana Callejo, Augusto Valdivia, Pedro Rocha, Javier Hernandez-Losa, Marta Sese, Oriol Mirallas, Laura Masfarré, Susana Cedrés, Alex Martinez-Marti, Rocío Caro-Consuegra, Enriqueta Felip   +20 more
doaj   +1 more source

Case of adenohypophysis adenocarcinoma according to postmortem results

Patologìâ, 2012
This article describes a case of rare disease – adenocarcinoma of adenohypophysis. A tumour had extremely small size and was accompanied by destruction of wall of the sella turcica and invasion of blood vessels, that resulted in development of thrombosis
N. Yu. Ozerova
doaj   +1 more source

Ocular tumors

, 2015
Intraocular tumors may leave the globe through vascular, neural, and transscleral routes and invade the periocular tissues and the orbit. These tumors primarily include retinoblastoma, uveal melanoma, and, to a lesser extent, malignant medulloepithelioma,
HADJISTILIANOU, THEODORA, Karcioglu, Zeynel A.   +1 more
core   +1 more source

MEN1 Deficiency‐Driven Activation of the β‐Catenin‐MGMT Axis Promotes Pancreatic Neuroendocrine Tumor Growth and Confers Temozolomide Resistance

Advanced Science
O6‐methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O6‐MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ).
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Zeng Ye, Qifeng Zhuo, Yan Wang, Desheng Jing, Guixiong Fan, Xuemin Chen, Yue Zhang, Chenjie Zhou, Jie Chen, Yi Qin, Xianjun Yu, Shunrong Ji   +16 more
doaj   +1 more source

Intracranial transplantation of the tumor induced by adenovirus type 12 in Syrian hamster--an experimental brain tumor model

, 1971
A method of intracranial transplantation of the tumor induced by adenovirus type 12 in syrian hamster has been described. The incidence of intracranial tumor development was 86 (90.5 %) out of 95 animals and the average survival time and tumor size at ...
Tabuchi, Kazuo
core   +1 more source

Integrative pathway analysis of gynecological tumors characterized by different chromosomal instability patterns [PDF]

, 2023
openGynecological tumors include four tumor types from TCGA: ovarian cancer (OV), cervical cancer (CESC), endometrial cancer (UCEC) and the rare uterine carcinosarcoma (UCS).
BORTOLATO, ANNA
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Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages [PDF]

, 2007
Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy.
Pollard, Jeffrey W, Bricard, Gabriel, Wang, Weigang, Deng, Yan, Porcelli, Steven A, Sellers, Rani, Lin, Elaine Y, Li, Jiu-feng   +7 more
core   +1 more source

FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis

Journal of Translational Medicine
Background Acute pancreatitis (AP) presents a significant clinical challenge with limited therapeutic options. The complex etiology and pathophysiology of AP emphasize the need for innovative treatments.
Amaya Lopez-Pascual, Eva Santamaria, Nuria Ardaiz, Iker Uriarte, Tiffany Palmer, Anne-Renee Graham, Celia Gomar, Roberto C. Barbero, M. Ujue Latasa, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Antonio Fontanellas, Carlos L. del Rio, Maite G. Fernandez-Barrena, Paolo G.V. Martini, Joshua R. Schultz, Pedro Berraondo, Matias A. Avila   +18 more
doaj   +1 more source

Soft tissue tumors: Lipoma / benign lipomatous tumors

, 2000
Review on Soft tissue tumors: Lipoma / benign lipomatous tumors, with data on clinics, and the genes ...
Mandahl, N
core   +1 more source

Pineal Region Tumors : Diagnosis and Treatment Options /

, 2009
The pineal region is an anatomic location where various intracranial tumors, in particular germ cell tumors and pineal parenchymal tumors, occur. Interestingly, pineal germ cell tumors are detected more frequently in Asian countries, including Japan ...
Kobayashi, T.
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