Results 211 to 220 of about 6,547,471 (339)

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib.

Proceedings of the National Academy of Sciences of the United States of America, 2004
W. Pao, V. Miller, M. Zakowski, J. Doherty, K. Politi, I. Sarkaria, Bhuvanesh Singh, R. Heelan, V. Rusch, L. Fulton, E. Mardis, Doris Kupfer, R. Wilson, M. Kris, H. Varmus   +14 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells

, 2022
Shaokui Chen, Ruixin Li, Yibo Chen, Chon‐Kit Chou, Zhexuan Zhang, Yang Yang, Ping Liao, Qingqing Wang, Xin Chen   +8 more
openalex   +1 more source

Survival of nervous system tumors in a Colombian population cancer registry. [PDF]

J Neurooncol
Albarracín Cárdenas CI, Caballero Rojas H, Ochoa Vera ME, Luna González ML, Rojas Díaz CA.   +4 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Circulating Tumor DNA to Predict Radiographic and Pathologic Response to Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer [PDF]

Stephanie Alden, Valerie Lee, Amol Narang, Jeffrey Meyer, Susan L. Gearhart, Eric S. Christenson   +5 more
openalex   +1 more source

Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas [PDF]

, 2014
Lars Rønn Olsen, Benito Campos, Ole Winther, Dennis C. Sgroi, Barry L. Karger, Vladimir Brusić   +5 more
openalex   +1 more source

Molecular profiling of endometrial cancer in Martinique reveals frequent CCNE1 amplification in poor prognosis tumors. [PDF]

Sci Rep
Labeau T, Loger JS, Jean-Laurent M, Hurlot Q, Jean-Laurent C, Chevallier L, Pennont S, Lise S, Amari S, Montlouis-Calixte J, Béra O, Vallard A, Randriamiarisoa H, Colomba E, Marlin R.   +14 more
europepmc   +1 more source

An endotoxin-induced serum factor that causes necrosis of tumors.

Proceedings of the National Academy of Sciences of the United States of America, 1975
E. Carswell, L. Old, R. Kassel, S. Green, N. Fiore, B. Williamson   +5 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source