Results 261 to 270 of about 3,717,417 (345)

Intra-abdominal Desmoid Tumors Mimicking Gastrointestinal Stromal Tumor (GIST) Recurrence: A Case Report. [PDF]

Cureus
Senaha Y, Matsubara T, Kaji S, Hayashi H, Hidaka M.   +4 more
europepmc   +1 more source

Nanoconjugation of PSMA-Targeting Ligands Enhances Perinuclear Localization and Improves Efficacy of Delivered Alpha-Particle Emitters against Tumor Endothelial Analogues

, 2015
Charles Zhu, Amey Bandekar, Michelle Sempkowski, Sangeeta Ray Banerjee, Martin G. Pomper, Frank Bruchertseifer, Aliyah Morgenstern, Stavroula Sofou   +7 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Oncolytic vaccinia virus encoding constitutively active EPAC remodels the tumor microenvironment to enhance therapeutic efficacy with chemotherapy and surgery. [PDF]

J Immunother Cancer
Boulton S, Singh S, Organ B, Thomas J, Rezaei R, Gill R, Vallati S, Guo Q, Dave J, Petryk J, De Souza CT, Austin B, He X, Gingrich A, Crupi MJF, Singaravelu R, Ilkow C, Bell JC.   +17 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Prediction of thyroid nodule properties and potential for malignant metastasis based on tumor pH. [PDF]

Thyroid Res
Liang XQ, Han T, Ma N, Mu T, Yan HN, Wu GY, Wang JY, Zhou H.   +7 more
europepmc   +1 more source

Benign Tumors and Tumorlike Lesions of the Pancreas

, 2016
Olca Baştürk, Gökçe Aşkan
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

DOG1 Immunohistochemical Expression in Normal and Neoplastic Canine Tissues: Is It Only a Marker for GISTs? [PDF]

Animals (Basel)
Morini M, Gobbo F, Mandrioli L, Bettini G.   +3 more
europepmc   +1 more source

Transformable self-delivered supramolecular nanomaterials combined with anti-PD-1 antibodies alleviate tumor immunosuppression to treat breast cancer with bone metastasis [PDF]

Xueying Liu, Hao Wang, Zhaofeng Li, Jiamei Li, Siqin He, Chuan Hu, Yujun Song, Huile Gao, Yi Qin   +8 more
openalex   +1 more source