Results 271 to 280 of about 6,372,774 (389)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma. [PDF]

Cancer Discov
Orlen M, Vostrejs WP, Sor R, McDevitt JC, Kemp SB, Kim IK, Kramer AB, Tovbis Shifrin N, Markosyan N, Clendenin C, Singh M, Quintana E, Menard M, Vonderheide RH, Stanger BZ.   +14 more
europepmc   +1 more source

Tumor Analogous to Spina Bifida [PDF]

Gilman Daveis
openalex   +1 more source

STUDIES ON A SUBSTANCE THAT PROMOTES TUMOR HOMOGRAFT SURVIVAL (THE "ENHANCING SUBSTANCE") [PDF]

, 1957
A.A. Kandutsch, U. Reinert-Wenck
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Systems biology successes and areas for opportunity in prostate cancer. [PDF]

Endocr Relat Cancer
Orman MV, Graham LS, Cramer SD, Costello JC.   +3 more
europepmc   +1 more source

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012

Neuro-Oncology, 2015
Q. Ostrom, H. Gittleman, J. Fulop, Max Liu, Rachel Blanda, Courtney Kromer, Yingli Wolinsky, C. Kruchko, J. Barnholtz-Sloan   +8 more
semanticscholar   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Merlin immunoreactivity fails to predict neurofibromatosis type 2 mutations in human meningiomas. [PDF]

J Neuropathol Exp Neurol
Tollefsen SE, Meta R, Solheim O, Mjønes P, Vestrheim I, Sjursen W, Torp SH.   +6 more
europepmc   +1 more source

TRANSPERITONEAL REMOVAL OF TUMORS OF THE BLADDER [PDF]

, 1908
CHARLES H. MAYO
openalex   +1 more source