Results 51 to 60 of about 2,238,052 (265)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Ocular tumors

, 2015
Intraocular tumors may leave the globe through vascular, neural, and transscleral routes and invade the periocular tissues and the orbit. These tumors primarily include retinoblastoma, uveal melanoma, and, to a lesser extent, malignant medulloepithelioma,
HADJISTILIANOU, THEODORA, Karcioglu, Zeynel A.   +1 more
core   +1 more source

Ovary: Epithelial tumors [PDF]

, 2003
Review on Ovary: Epithelial tumors, with data on clinics, and the genes ...
L Lee-Jones, Lee-Jones, L, Lee-Jones, Lisa   +2 more
core   +1 more source

Incidence and distribution of jaw pathologies among 0–15 years age group at a tertiary rural health-care center of Maharashtra: A retrospective study of 10 years

Contemporary Clinical Dentistry, 2020
Objective: This study was undertaken to investigate the prevalence of intraosseous jaw lesions among pediatrics (0–15 years of age) in a rural health-care center of Maharashtra and to determine the most common types of lesions and their distribution ...
Parul Tandon, Seemit Shah, Anuj Dadhich, Harish Saluja, Himanshu Chauhan   +4 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Somatic copy number alterations profiling in non-small cell lung cancer and their correlation with clinical efficacy in first-line treatment

Genome Medicine
Background Immune checkpoint inhibitors (ICI) are the current standard-of-care first-line treatment for advanced non-small cell lung cancer (NSCLC) without actionable genomic alterations.
Ilaria Priano, Ramon Amat, Caterina Carbonell, Aina Arbusà-Roca, Patricia Iranzo, Nuria Pardo, Mireia Soleda, Gerard Romero-Sola, Barbara Sinigaglia, Sara Polo-Alonso, Ana Callejo, Augusto Valdivia, Pedro Rocha, Javier Hernandez-Losa, Marta Sese, Oriol Mirallas, Laura Masfarré, Susana Cedrés, Alex Martinez-Marti, Rocío Caro-Consuegra, Enriqueta Felip   +20 more
doaj   +1 more source

Prediction of bladder tumor relapse based on the risk factors and characteristics of the treatment [PDF]

Medičnì Perspektivi, 2015
Objectives. To investigate the possibility of predicting recurrence of bladder tumors based on the clinical and morphological features of the disease and preoperative intravesical instillation of probiotic Aerococcus viridans 167.
Molchanov R.N., Blyuss O.B.
doaj  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

MEN1 Deficiency‐Driven Activation of the β‐Catenin‐MGMT Axis Promotes Pancreatic Neuroendocrine Tumor Growth and Confers Temozolomide Resistance

Advanced Science
O6‐methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O6‐MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ).
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Zeng Ye, Qifeng Zhuo, Yan Wang, Desheng Jing, Guixiong Fan, Xuemin Chen, Yue Zhang, Chenjie Zhou, Jie Chen, Yi Qin, Xianjun Yu, Shunrong Ji   +16 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source