Results 141 to 150 of about 1,360,599 (360)

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C [PDF]

open access: yes, 2007
The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Intra-Operative Irradiation in Abdominal and Cerebral Tumours [PDF]

open access: bronze, 1971
Manabu Abe   +4 more
openalex   +1 more source

Cancer stem cell and epithelial mesenchymal transition in chemo resistance of canine solid tumours [PDF]

open access: diamond, 2023
Lavanya Killi   +5 more
openalex   +1 more source

Skin tumours

open access: yesJournal of Cutaneous and Aesthetic Surgery, 2012
Khandpur, Sujay, Ramam, M
openaire   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The retinoblastoma protein contributes to maintaining the stability of HPV E7 in cervical cancer cells

open access: yesJournal of Virology
High-risk human papillomaviruses (HR HPV)-16 and -18, and other closely related subtypes, are associated with at least 90% of human cervical cancers.
Ifeoluwa Gbala   +2 more
doaj   +1 more source

Bayesian Calibration, Validation and Uncertainty Quantification for Predictive Modelling of Tumour Growth: A Tutorial

open access: green, 2017
Joe Collis   +6 more
openalex   +2 more sources

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