YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen +8 more
wiley +1 more source
The Human Penile Fibro-Vascular Assembly Requires the Integrity of Ten Fibro-Ligaments. [PDF]
Chen HS +7 more
europepmc +1 more source
Implications of inflammation and sex in lower extremity arterial disease
The graphical abstract illustrates the role of inflammation and sex‐related differences in lower extremity artery disease (LEAD). Key inflammatory biomarkers associated with LEAD include C‐reactive protein (CRP), fibrinogen, interleukin‐6 (IL‐6), and D‐dimer, which contribute to vascular inflammation and atherosclerotic plaque formation in lower limb ...
Katja Schnidrig +7 more
wiley +1 more source
An improved porcine model of infrarenal abdominal aortic aneurysm. [PDF]
Stei M +25 more
europepmc +1 more source
We analysed collagen XV expression in myocardial infarct samples and assessed how its deficiency affects cardiac responses, such as fibrogenesis and tissue stiffness. In mice, damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel ...
Sanna‐Maria Karppinen +15 more
wiley +1 more source
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley +1 more source
New Insights into the Mucus-Secreting Cells in the Proventriculus of 10 Day Old Ross 308 Broiler Chickens-A Qualitative RGB Color Study by Histochemical Assessment. [PDF]
Rus V, Matei-Lațiu MC, Gal AF.
europepmc +1 more source
Molecular pathology of testicular germ cell tumours: an update for practicing pathologists
Molecular testing for isochromosome 12p is usually only necessary in difficult cases that encompass metastases or recurrent diseases including somatic‐type malignancies. So far, no breaking progress has been made in the field of targeted therapy as TGCTs only rarely show targetable molecular alterations.
Alexander Fichtner +3 more
wiley +1 more source
[Histopathological diagnosis of intestinal motility disorders: Hirschsprung disease and differential diagnoses]. [PDF]
Menter T.
europepmc +1 more source
The role of suprarenal side branches in dissecting abdominal aortic aneurysm formation in angiotensin II-infused mice [PDF]
Fraga-Silva, Rodrigo +4 more
core +1 more source

