Results 31 to 40 of about 40,952 (269)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Calculation of process load of deep-buried asymmetric multi-arch tunnels
Yantu gongcheng xuebao, 2020 Deep-buried asymmetric multi-arch tunnels have complex mechanical features such as geometric asymmetry, structural asymmetry and left-to-right load asymmetry. There have been no relevant codes and standards for the process of construction on the pressure
GAO Hong-jie , HE Ping , CHEN Zheng
doaj +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed +6 more
wiley +1 more source
Tunneling of Hydrogen and Deuterium Atoms on Interstellar Ices (Ih and ASW)
Frontiers in Astronomy and Space Sciences, 2021 Model calculations are performed to investigate the kinetic isotope effect of hydrogen and deuterium atom diffusion on hexagonal ice and amorphous solid water. Comparisons with experimental results by Kuwahata et al. (Phys. Rev. Lett., Sep. 2015, 115 (13)
Gunnar Nyman
doaj +1 more source
The PRIMA Thesaurus for Materials Science and Engineering
Advanced Engineering Materials, EarlyView.The PRIMA Thesaurus is a structured vocabulary designed to improve how materials science data is described and shared. Developed with input from multiple experts, it enables clear documentation of research workflows, data exchange, and reuse across platforms.
Rossella Aversa +8 more
wiley +1 more source
Settlement prediction of undercrossing semicircular tunnel-pile set up in soft clay soil
Scientific ReportsSoil–structure interactions commonly induce displacements, with settlements in weak soils becoming increasingly significant under growing urbanization, making it important to minimize them to prevent structural defects.
Norman Burua Adriko +3 more
doaj +1 more source
Complexity, 2018 Blasting in water-conveyance tunnels that cross rivers is vital for the safety and stability of embankments. In this work, a tunnel project that crosses the Yellow River in the north district of the first-phase Eastern Line of the South-to-North Water ...
Xian-qi Zhou +5 more
doaj +1 more source
IEEE Open Journal of Nanotechnology, 2022 We report on optical and electrical properties of amorphous In-Ga-Mg-O (a-IGMO) films and characteristics of a-IGMO channel thin-film transistors which went through the reductive post-annealing process.
Hisato Yabuta +3 more
doaj +1 more source