Results 31 to 40 of about 123,251 (318)

Investigation of Thiocarbamates as Potential Inhibitors of the SARS-CoV-2 Mpro

open access: yesPharmaceuticals, 2021
In the present study we tested, using the microscale thermophoresis technique, a small library of thionocarbamates, thiolocarbamates, sulfide and disulfide as potential lead compounds for SARS-CoV-2 Mpro drug design. The successfully identified binder is
Katarzyna Papaj   +11 more
doaj   +1 more source

A diode device combining lateral field-effect transport and vertical tunneling in a multi-quantum-well heterostructure [PDF]

open access: yes, 1992
The authors discuss an electronic device with asymmetric contacts to a InGaAs-InP multilayer heterostructure. Current enters via an alloyed ohmic contact into the quantum wells (QWs) and flows laterally along capacitively coupled channels.
Marczewski, J.   +5 more
core   +1 more source

TUNNEL VENTILATION MODELLING IN SLOPED TUNNELS

open access: yesChemical Engineering Transactions, 2009
Not available.
PALAZZI, EMILIO   +3 more
openaire   +2 more sources

Exploring Solanum tuberosum Epoxide Hydrolase Internal Architecture by Water Molecules Tracking

open access: yesBiomolecules, 2018
Several different approaches are used to describe the role of protein compartments and residues in catalysis and to identify key residues suitable for the modification of the activity or selectivity of the desired enzyme.
Karolina Mitusińska   +4 more
doaj   +1 more source

Evidence for the Josephson Effect in Quantum Hall Bilayers [PDF]

open access: yes, 2004
This thesis presents tunneling measurements on bilayer two-dimensional (2D) electrons systems in GaAs/AlGaAs double quantum wells. 2D-2D tunneling is applied here as a probe of the inter-layer correlated quantum Hall state at total Landau level filling
Spielman, Ian Bairstow
core   +1 more source

Investigations of Nanoscale Variations in Spin and Charge Transport in Manganites and Organic Semiconductors Using Spin Polarized Scanning Tunneling Spectroscopy [PDF]

open access: yes, 2010
Spintronics is a new class of spin-dependent electronics with great potential for nonvolatile memory and logic technology. Additionally, spintronics may be combined with optoelectronic applications to achieve higher efficiency and novel capabilities. All
Hughes, Cameron Richard
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tunneling and Tax Aggressiveness [PDF]

open access: yes, 2020
In Brazil, there are no mechanisms to identify cases where controlling shareholders might be using tax aggressiveness as a strategy to expropriate value from minority shareholders, the practice known as tunneling.
Israel Lucas de Oliveira Aguiar,Felipe Ramos Ferreira,Silvania Neris Nossa,Edvan Soares de Oliveira
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Oscillator tunneling dynamics in the Rabi model

open access: yes, 2014
Funding support from the National Science Foundation and the Leverhulme Trust is acknowledged.The familiar Rabi model, comprising a two-level system coupled to a quantum harmonic oscillator, continues to produce rich and surprising physics when the ...
Gea-Banacloche, J.   +2 more
core   +1 more source

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