Results 211 to 220 of about 3,817,942 (325)

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, Volume 36, Issue 4, July 2026.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

A Comparative Evaluation of GPT-4 Turbo and Gemini-Pro in Medical Licensing Exams: Enhancing Artificial Intelligence's Role in Medical Education. [PDF]

Cureus
Sussan TT, Sussan RJ, Atkinson AG, Atkinson IH, Cunningham K, Eckroth J, Miller LB, Wei T.   +7 more
europepmc   +1 more source

A Phase 1, Open‐Label, Randomized Study to Investigate the Pharmacokinetics and Safety of Multiple Doses of Intranasal Naloxone in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 7, July 2026.
ABSTRACT This was a Phase 1, open label, randomized, crossover study to evaluate the safety and pharmacokinetics of multiple doses of intranasal naloxone (NCT05377255). Twenty‐four healthy participants were enrolled at a single site in the US to one of two sequences.
David Cassie, Bob Warnock, Faisal Akhtar, Duncan McCloskey, David Wyatt   +4 more
wiley   +1 more source

Evaluating the reliability of large language models for clinical data extraction in bladder cancer prognosis. [PDF]

Sci Rep
Sun D, Hadjiiski L, Bruno G, Gormley J, Chan HP, Caoili EM, Cohan RH, Alva A, Mihalcea R, Zhou C, Gulani V.   +10 more
europepmc   +1 more source

How Precise Is Predictive Coding for Things We Hear? Mismatch Negativity With Shepard Tones

European Journal of Neuroscience, Volume 64, Issue 1, July 2026.
MMN amplitudes to unpredictable tones in a discrete Shepard scale were more negative the farther the unpredictable tones were from the predicted note and more negative for tones that were less than the expected note. We conclude that the predictive model for a discrete Shepard scale has a sensitivity to tones less than one third of a semitone and is ...
Urte Roeber, Robert P. O'Shea
wiley   +1 more source

ChatGPT-5 versus other mainstream large language models in core diabetic retinopathy patient queries. [PDF]

Front Cell Dev Biol
Cang X, Ni M, Song C, Zhao J, Guo Y, Zou Y, Zhang Z, Jiang L.   +7 more
europepmc   +1 more source

Applications of ChatGPT in the Health Sector: A Systematic Literature Review

Expert Systems, Volume 43, Issue 7, July 2026.
ABSTRACT The integration of large language models, particularly ChatGPT, into healthcare has attracted increasing attention due to their potential to support medical education, clinical decision‐making, administrative workflows, patient communication and clinical documentation.
Alejandro Martínez‐Burgos, Elena Enamorado‐Díaz, Javier Jesús Gutiérrez‐Rodríguez, Julián A. García‐García   +3 more
wiley   +1 more source

A multi-stage large language model framework for extracting suicide-related social determinants of health. [PDF]

Commun Med (Lond)
Wang S, Wei Y, Ma H, Lovitt M, Deng K, Meng Y, Xu Z, Zhang J, Xiao Y, Ding Y, Xu X, Ghosh J, Peng Y.   +12 more
europepmc   +1 more source

FcMAPK4‐phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression

Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 2264-2284, July 2026.
In Ficus carica fruit, the MAP kinase FcMAPK4 phosphorylates the NAC transcription factor FcNOR, which cooperates with ethylene response factor FcERF5 to activate the pectin degradation gene FcPG12, thereby promoting rapid softening of fig fruit. ABSTRACT Rapid softening of fig (Ficus carica L.) fruit during ripening leads to extremely short shelf life;
Yuan Wang, Zhiyi Fan, Yining Wang, Alexander Vainstein, Yuexuan Qiu, Yinan Sun, Huiqin Ma   +6 more
wiley   +1 more source

Limitations in Chest X-Ray Interpretation by Vision-Capable Large Language Models, Gemini 1.0, Gemini 1.5 Pro, GPT-4 Turbo, and GPT-4o. [PDF]

Diagnostics (Basel)
Chen CH, Chen CW, Hsieh KY, Huang KE, Lai HY.   +4 more
europepmc   +1 more source