Results 261 to 270 of about 2,501,833 (347)

High-performance automated abstract screening with large language model ensembles. [PDF]

open access: yesJ Am Med Inform Assoc
Sanghera R   +9 more
europepmc   +1 more source

The Quorum Sensing Regulated sRNA Lrs1 Is Involved in the Adaptation to Low Iron in Pseudomonas aeruginosa

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 2, April 2025.
The quorum sensing regulated sRNA Lrs1 participates in the adaptation of Pseudomonas aeruginosa in low iron by downregulating the siderophore pyochelin, the Quorum Sensing system PQS, and its associated virulence factor phenazines. ABSTRACT Iron is an essential nutrient for microbial growth. The opportunistic pathogen Pseudomonas aeruginosa can survive
Dimitra Panagiotopoulou   +7 more
wiley   +1 more source

“Dark taxonomy”: A new protocol for overcoming the taxonomic impediments for dark taxa and broadening the taxon base for biodiversity assessment

open access: yesCladistics, Volume 41, Issue 2, Page 223-238, April 2025.
Abstract We are entering the sixth mass extinction with little data for “dark taxa”, although they comprise most species. Much of the neglect is due to the fact that conventional taxonomic methods struggle with handling thousands of specimens belonging to hundreds of species. We thus here propose a new strategy that we call “dark taxonomy”.
Rudolf Meier   +7 more
wiley   +1 more source

Supervised machine learning compared to large language models for identifying functional seizures from medical records

open access: yesEpilepsia, Volume 66, Issue 4, Page 1155-1164, April 2025.
Abstract Objective The Functional Seizures Likelihood Score (FSLS) is a supervised machine learning–based diagnostic score that was developed to differentiate functional seizures (FS) from epileptic seizures (ES). In contrast to this targeted approach, large language models (LLMs) can identify patterns in data for which they were not specifically ...
Wesley T. Kerr   +9 more
wiley   +1 more source

Imeglimin, unlike metformin, does not perturb differentiation of human induced pluripotent stem cells towards pancreatic β‐like cells and rather enhances gain in β cell identity gene sets

open access: yesJournal of Diabetes Investigation, Volume 16, Issue 4, Page 584-597, April 2025.
Metformin is used in some countries as treatment for hyperglycemia in pregnancy (HIP), and beneficially improves maternal glucose metabolism and reduces perinatal complications, although metformin could impede pancreatic β cell development via impaired mitochondrial function.
Tasuku Imada   +6 more
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

On opportunities and challenges of large multimodal foundation models in education. [PDF]

open access: yesNPJ Sci Learn
Küchemann S   +19 more
europepmc   +1 more source

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