Results 271 to 280 of about 2,501,833 (347)

A Systematic Targeted Genetic Screen Identifies Proteins Involved in Cytoadherence of the Malaria Parasite P. falciparum

Molecular Microbiology, Volume 123, Issue 4, Page 330-343, April 2025.
In silico workflow for selection of genes targeted in this study. We have identified a number of proteins involved in host cell modification by malaria parasites. Furthermore, we highlight a number of genes that appear to be essential for blood‐stage survival of these parasites.
Nina Küster, Lena Roling, Ardin Ouayoue, Katharina Steeg, Jude M. Przyborski   +4 more
wiley   +1 more source

Few-shot biomedical NER empowered by LLMs-assisted data augmentation and multi-scale feature extraction. [PDF]

BioData Min
Zhao D, Mu W, Jia X, Liu S, Chu Y, Meng J, Lin H.   +6 more
europepmc   +1 more source

Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth

Plant Biotechnology Journal, Volume 23, Issue 4, Page 1230-1242, April 2025.
Summary The first step in chloroplast de novo fatty acid synthesis is catalysed by acetyl‐CoA carboxylase (ACCase). As the rate‐limiting step for this pathway, ACCase is subject to both positive and negative regulation. In this study, we identify a Chlamydomonas homologue of the plant carboxyltransferase interactor 1 (CrCTI1) and show that this protein
Zhongze Li, Minjae Kim, Jose Roberto da Silva Nascimento, Bertrand Legeret, Gabriel Lemes Jorge, Marie Bertrand, Fred Beisson, Jay J. Thelen, Yonghua Li‐Beisson   +8 more
wiley   +1 more source

Network of artificial olfactory receptors for spatiotemporal monitoring of toxic gas. [PDF]

Sci Adv
Baek Y, Bae B, Yang J, Cho W, Sim I, Yoo G, Chung S, Heo J, Lee K.   +8 more
europepmc   +1 more source

Cost‐Effective and Highly Scalable Typing of HLA Classes I and II Genes of up to 96 Individuals Using Nanopore Sequencing

HLA, Volume 105, Issue 4, April 2025.
ABSTRACT HLA typing of large donor registries and biobanks as well as acute single patient/donor samples remains expensive, slow and logistically challenging, despite recent developments in the field. We have tested and validated a cost‐effective, accurate and highly scalable method for typing specific genes in the HLA region.
Frederikke Byron Pedersen, Anne Werner Hauge, Jacob Flemming Hansen, Laura Studnitz Andersen, Signe Blomsterberg, Helle Bruunsgaard   +5 more
wiley   +1 more source

Autonomous medical evaluation for guideline adherence of large language models. [PDF]

NPJ Digit Med
Fast D, Adams LC, Busch F, Fallon C, Huppertz M, Siepmann R, Prucker P, Bayerl N, Truhn D, Makowski M, Löser A, Bressem KK.   +11 more
europepmc   +1 more source

Asking an AI for salary negotiation advice is a matter of concern: Controlled experimental perturbation of ChatGPT for protected and non-protected group discrimination on a contextual task with no clear ground truth answers. [PDF]

PLoS One
Geiger RS, O'Sullivan F, Wang E, Lo J.
europepmc   +1 more source

The Two Word Test as a semantic benchmark for large language models. [PDF]

Sci Rep
Riccardi N, Yang X, Desai RH.
europepmc   +1 more source

Large language model based mutations in genetic improvement. [PDF]

Autom Softw Eng
Brownlee AEI, Callan J, Even-Mendoza K, Geiger A, Hanna C, Petke J, Sarro F, Sobania D.   +7 more
europepmc   +1 more source

LOGIC: LLM-originated guidance for internal cognitive improvement of small language models in stance detection. [PDF]

PeerJ Comput Sci
Lee W, Lee J, Kim H.
europepmc   +1 more source