Results 111 to 120 of about 22,376 (246)

Ventricular Synchrony in Targeted Right Ventricular Septal Pacing: A Prospective Paired Comparison to Apical Placement

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background/Objectives Right ventricular (RV) apical pacing, the standard pacing approach, often induces ventricular dyssynchrony, potentially impairing cardiac function. This study aims to investigate whether targeted RV septal pacing, guided by functional electrophysiological feedback during implantation, reduces ventricular dyssynchrony ...
Bianca Iulia Catrina   +5 more
wiley   +1 more source

A Three Amino Acid Sequence Gates Protein Stability Control of bHLH104 and Iron Uptake in Arabidopsis thaliana

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Iron (Fe) homeostasis is regulated to prevent iron imbalance, with the help of redundant basic helix‐loop‐helix (bHLH) IVc transcription factors that can be controlled by Fe‐binding E3 ligases such as BRUTUS (BTS) in Arabidopsis thaliana.
Dibin Baby   +5 more
wiley   +1 more source

What Does “STEM” Mean to Students? Exploring the Interplay Between Self‐Efficacy, Extracurricular Activities, Subject Associations, and Academic Intentions in Secondary School

open access: yesSchool Science and Mathematics, EarlyView.
ABSTRACT Despite extensive discourse in educational research and practice, inconsistencies persist in students' perception of, and engagement with, STEM subjects. This study investigates how secondary school students perceive STEM disciplines, and which factors modulate their self‐efficacy and academic intentions. The survey (n = 853) revealed a widely
Alessandro Siani, Claudiu Dacin
wiley   +1 more source

The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia in high‐altitude deer mice (Peromyscus maniculatus)

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia has been contentious. Many high‐altitude natives have greater haemoglobin–O2 affinity (lower P50, the O2 pressure at 50% haemoglobin saturation) than their low‐altitude counterparts, but the advantages of this change for aerobic metabolism have often remained
Kayla M. Garvey, Graham R. Scott
wiley   +1 more source

microRNA‐145‐5p regulates P‐glycoprotein and breast cancer resistance protein in primary human fetal brain endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Drug transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) at the blood–brain barrier (BBB) protect the rapidly developing fetal brain. We investigated the role of microRNA‐145‐5p (miR‐145‐5p) microRNA (miRNA) in regulating these key transporters in primary human fetal brain endothelial cells in vitro. We
Phetcharawan Lye   +5 more
wiley   +1 more source

PRECISE: Reducing the bias of LLM evaluations using prediction‐powered ranking estimation

open access: yesAI Magazine, Volume 47, Issue 4, Winter 2026.
Abstract Evaluating the quality of search systems traditionally requires a significant number of human relevance annotations. In recent times, several systems have explored the usage of Large Language Models (LLMs) as automated judges for this task while their inherent biases prevent direct use for metric estimation.
Abhishek Divekar, Anirban Majumder
wiley   +1 more source

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