Results 171 to 180 of about 398,912 (227)

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

open access: yesEpilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi   +8 more
wiley   +1 more source

A Numerical Investigation of the Effects of Piston Bowl Geometry and Spray Angle on Combustion, Performance and Emission of a Diesel Engine

open access: yesEnergy Science &Engineering, EarlyView.
A piston bowl's design and spray angle improve air‐fuel mixing, resulting in more complete combustion and higher efficiency. Ansys Forte 2023 R1 a CFD software was used to analyze the effects of five combustion chamber geometries of cylinder, modified re‐entrant, re‐entrant, double‐stepped, and stepped on engine performance, combustion, and emission ...
Md. Nazmul Haque   +7 more
wiley   +1 more source

Multi‐Objective RSM Optimization of Emission and Performance Characteristics in a Diesel Engine Fueled With BaTiO3 Nano‐Enhanced Jojoba Biodiesel

open access: yesEnergy Science &Engineering, EarlyView.
This study uses response surface methodology to optimize Jojoba biodiesel blended with BaTiO3 nanoparticles in a single‐cylinder diesel engine. Results show that ~48.95–51.31 ppm of BaTiO3 achieves balanced performance and emission, decreasing CO and NOx while increasing torque and brake thermal efficiency.
Arif Savaş   +4 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

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