Results 51 to 60 of about 618 (258)

A Superlubricated Magnetically Steerable Microcatheter with Integrated Optical and Fluidic Channels

Advanced Robotics Research, EarlyView.
A magnetically steerable microcatheter with integrated optical and fluidic channels is developed for multifunctional navigation in tortuous anatomical environments. A surface‐grafted hydrogel coating enables low‐friction actuation. The device demonstrates stable light and fluid delivery during magnetic manipulation, offering a compact platform for ...
Yuntian Du, Ruokun He, Luqi Li, Hesheng Wang, Zhuo‐Chen Ma, Bing Han   +5 more
wiley   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Experimental investigation and data-driven prediction of gearbox churning loss in high-rotational-speed flow regimes

Engineering Science and Technology, an International Journal
The churning loss in gearboxes, generated by gears rotating in a lubricant bath, significantly reduces power transmission efficiency. Conventional empirical models exhibit large prediction errors in high-rotational-speed flow regimes, where complex ...
Donggun Lee, Sung-Bo Shim, Suchul Kim
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Flow Characteristics and Experimental Verification of T-Groove Dry Gas Seal Under Different Flow States

Lubricants
With the improvement of dry gas seal efficiency in high-parameter fields, the flow pattern of gas film lubrication is complicated. Based on gas lubrication theory, the Reynolds equation of compressible gas was established with a bidirectional T-groove ...
Lanxia Zhang, Xuexing Ding, Shipeng Wang, Shuai Zhang   +3 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

CFD Simulations of an Air-Water Bubble Column: Effect of Luo Coalescence Parameter and Breakup Kernels

Frontiers in Chemistry, 2017
In this work, CFD simulations of an air-water bubbling column were performed and validated with experimental data. The superficial gas velocities used for the experiments were 0.019 and 0.038 m/s and were considered as an homogeneous regime.
Alizeb Hussain Syed, Micael Boulet, Tommaso Melchiori, Jean-Michel Lavoie   +3 more
doaj   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

A computational review of various inter-facial forces in fully developed multiphase fluid under different flow patterns in vertical column

Propulsion and Power Research
The main contribution of this work is a comprehensive overview of the many years of research on various inter-facial forces with distinct flow structure transitions in liquid-gas multiphase flow in vertical columns.
Faisal Shah, Desheng Zhang, Linlin Geng
doaj   +1 more source

Study on the Gas Film Flow Field and its Influencing Factors at the Outlet of the Orifice of the Aerostatic Bearing

Shock and Vibration, 2020
In order to further explore and study the influencing factors and regulars of the gas film flow field at the outlet of the orifice of the aerostatic bearing, the large eddy simulation method was used to calculate the N-S equation in the calculation area ...
Zhi-Wei Lu, Jun-An Zhang, Bo Liu
doaj   +1 more source