Results 191 to 200 of about 15,562 (263)

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Bridging the Energy Balance Gap in Eddy-Covariance Measurements: Insights From Standardized Network Data. [PDF]

Glob Chang Biol
Nicolini G, Durden D, Di Fiore L, Florian C, Sabbatini S, Gielen B, Iserbyt A, Loubet B, Mammarella I, Mariotti A, Op de Beeck M, Slemmons C, Trotta C, Young A, Chabbi A, Feigenwinter I, Heinesch B, Kowalska N, Mauder M, Šigut L, van der Molen M, Bastos Campos F, Berveiller D, Brümmer C, Cuntz M, Domec JC, Dumont B, Fares S, Gianelle D, Jensen R, Kalalian C, Kljun N, Lange H, Limousin JM, Lundin E, Manco A, Montagnani L, Nemitz E, Peichl M, Rinne E, Roland M, Schmidt M, Simioni G, Thomas A, Vincke C, Papale D.   +45 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Vortex-Based Cavitation Devices for Continuous Emulsification: Influence of the Device Design, Scale-Up, and Scale-Out. [PDF]

Ind Eng Chem Res
Gode A, Kourousis K, Ranade VV.
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Study of sand particle motion characteristics and distribution patterns in a helical-blade multiphase pump. [PDF]

Sci Rep
Zhao X, Shi G, Cui Z, Zhang Y.
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

A Miniaturized Multi-Parameter Synchronous Observation System for In Situ Ocean Turbulence Measurement. [PDF]

Sensors (Basel)
Ouyang W, Zhang Z, Jing J.
europepmc   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Study on the influence of key parameters of sand emission on dust flux based on multi-source data. [PDF]

Sci Rep
Maihamuti M, Huo W, Liu Y, Wang Y, Yang F, Zhou C, Yang X, Mamtimin A, Maihemuti M.   +8 more
europepmc   +1 more source