Results 131 to 140 of about 2,629,242 (377)

Comparative study of cutting force development during the machining of un-hybridized and hybridized ZA43 based metal matrix composites

open access: yesJournal of the Mechanical Behavior of Materials, 2019
In the present study, turning of two grades of composites such as ZA43 silicon carbide and ZA43 silicon carbide and graphite was carried out. The fabrication of both categories of composites were done using stir casting technique.
Kumar K. J. Santhosh   +1 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Magnetic heading reference [PDF]

open access: yes, 1977
This invention employs a magnetometer as a magnetic heading reference for a vehicle such as a small aircraft. The magnetometer is mounted on a directional dial in the aircraft in the vicinity of the pilot such that it is free to turn with the dial about ...
Garner, H. D.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Comparative Analysis of Dry, Minimum Quantity Lubrication, and Nano-Reinforced Minimum Quantity Lubrication Environments on the Machining Performance of AZ91D Magnesium Alloy

open access: yesMachines
This study investigates the machining performance of AZ91D magnesium alloy under three different cooling environments: dry, minimum quantity lubrication (MQL), and nano-reinforced MQL (NanoMQL) with multi-walled carbon nanotubes. Turning experiments were
Berat Baris Buldum   +2 more
doaj   +1 more source

Characterizations of generalized John domains in $\mathbb{R}^n$ via metric duality

open access: yes, 2018
Using the metric duality theory developed by Vaisala, we characterize generalized John domains in terms of higher dimensional homological bounded turning for its complement under mild assumptions.
Goldstein, Pawel   +3 more
core  

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Internet: turning science communication inside-out? [PDF]

open access: yes, 2008
In the four decades since two university computers were first linked to each other over the prototype internet, scientific researchers have been innovators, early adopters and prolific adapters of internet technologies.
Trench, Brian
core  

Turning Cold into Hot: Firing up the Tumor Microenvironment.

open access: yesTrends in Cancer, 2020
Q. Duan   +3 more
semanticscholar   +1 more source

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