Results 91 to 100 of about 5,912,428 (312)

What the Recovery Movement Tells Us About Prefigurative Politics

open access: yesJournal of Social and Political Psychology, 2016
The concept of prefigurative politics has re-emerged following recent worldwide uprisings, such as the Occupy movement, to which this concept has been applied.
Melinda Beckwith   +2 more
doaj   +1 more source

Reappraising maturity models in e-Government research: The trajectory-turning point theory

open access: yesJournal of strategic information systems, 2019
Drawing on the notion of alignment, this paper endeavors to reappraise e-Government maturity models in the English system of criminal justice. It argues that e-Government maturity models are characterized by relatively-stable trajectories which are ...
F. Iannacci   +3 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Raising the profile of public health ethics in Australia: time for debate

open access: yesAustralian and New Zealand Journal of Public Health, 2004
This paper argues for greater dialogue on public health ethics. There has been little discussion in Australia about the significant ethical dilemmas in this field, and there is no agreed framework for analysing and responding to these challenges.
Craig L. Fry   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Patient-specific record linkage between emergency department and hospital admission data for a cohort of people who inject drugs: methodological considerations for frequent presenters

open access: yesBMC Medical Research Methodology, 2020
Background People who inject drugs (PWID) have been identified as frequent users of emergency department (ED) and hospital inpatient services. The specific challenges of record linkage in cohorts with numerous administrative health records occurring in ...
Rehana Di Rico   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Highly sensitive gas refractometers based on optical microfiber modal interferometers operating at dispersion turning point.

open access: yesOptics Express, 2018
In most fiber-optic gas sensing applications where the interested refractive index (RI) is ~1.0, the sensitivities are greatly constrained by the large mismatch between the effective RI of the guided mode and the RI of the surrounding gaseous medium ...
N. Zhang   +7 more
semanticscholar   +1 more source

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