Results 21 to 30 of about 6,278 (263)

Compelled Turnout and Democratic Turnout: Why They Are Different

open access: yesPolitical Studies, 2023
One strategy in defence of compulsory voting is based on what I call the non-instrumental value of high turnout: the idea that almost-universal participation in elections is valuable per se. This article argues that we do not have democratic reasons to value compelled turnout.
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Turnout Fault Diagnosis through Dynamic Time Warping and Signal Normalization

open access: yesJournal of Advanced Transportation, 2017
Turnout is one key fundamental infrastructure in the railway signal system, which has great influence on the safety of railway systems. Currently, turnout fault diagnoses are conducted manually in China; engineers are obliged to observe the signals and ...
Shize Huang   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Features of mathematical modeling of dynamic processes of car passing railroad turnouts

open access: yesВестник Научно-исследовательского института железнодорожного транспорта, 2020
Dimensions and tolerances in the “wheelset — railway track” system are interconnected, since the normative values of geometric parameters and shape of the elements of the wheelsets and the track's upper structure are directly de pendent. In 2018– 2019 in
Yu. S. Romen   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Control Algorithm of Train Autonomous Control System in Turnout Safety Zones

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Unlike the existing CBTC (communication-based train control) system control mechanism, the ATC (autonomous train control) system achieves autonomous train operation by directly controlling wayside resources.
Yanfeng WANG, Zehui XIE
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

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