Results 21 to 30 of about 23,805 (261)

Engineering solutions to improve conditions and smoothness of train traffic on turnout switches

Вестник Научно-исследовательского института железнодорожного транспорта
Introduction. The currently used turnout switches geometries provided for the development and serial production of the main types of turnout equipment that ensure the transport process on the Russian railways.
Boris E. Glyuzberg, Pavel V. Tregubchak, Il'ya V. Tsittser   +2 more
doaj   +1 more source

Is all campaigning equally positive? The impact of district level campaigning on voter turnout at the 2010 British general election [PDF]

, 2015
Copyright © The Author(s) 2015.. A significant comparative literature suggests that campaigning efforts by political parties impact positively, both in terms of mobilization and turnout. However, effects are not uniform.
Fieldhouse, Edward; id_orcid, Fisher, JT, Fieldhouse, Edarwd, Pattie, C, Pattie, C.J., Pattie, Charles, Fieldhouse, E, Cutts, David, Johnston, R.J., Fisher, J., Fieldhouse, E.A., Johnston, Ron, Johnston, R, Cutts, D, Fisher, Justin, Cutts, D.   +15 more
core   +1 more source

Compelled Turnout and Democratic Turnout: Why They Are Different

Political Studies, 2023
One strategy in defence of compulsory voting is based on what I call the non-instrumental value of high turnout: the idea that almost-universal participation in elections is valuable per se. This article argues that we do not have democratic reasons to value compelled turnout.
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Turnout Fault Diagnosis through Dynamic Time Warping and Signal Normalization

Journal of Advanced Transportation, 2017
Turnout is one key fundamental infrastructure in the railway signal system, which has great influence on the safety of railway systems. Currently, turnout fault diagnoses are conducted manually in China; engineers are obliged to observe the signals and ...
Shize Huang, Fan Zhang, Rongjie Yu, Wei Chen, Fei Hu, Decun Dong   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Features of mathematical modeling of dynamic processes of car passing railroad turnouts

Вестник Научно-исследовательского института железнодорожного транспорта, 2020
Dimensions and tolerances in the “wheelset — railway track” system are interconnected, since the normative values of geometric parameters and shape of the elements of the wheelsets and the track's upper structure are directly de pendent. In 2018– 2019 in
Yu. S. Romen, B. E. Glyuzberg, E. A. Timakova, V. A. Bykov   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source