Results 251 to 260 of about 28,094 (310)

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

General elections in Poland (1990-2024) in the unified territorial aggregation: GeoElections Poland 1.0. [PDF]

Sci Data
Śleszyński P, Kowalski M.
europepmc   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Revisiting the Sectoral Cleavage in Canada: Evidence From the Canadian Election Studies. [PDF]

Can Rev Sociol
Polacko M, Graefe P, Kiss S.
europepmc   +1 more source

Water/Ionic Liquid Hybrid Electrolyte for High Cycling Stability and Low‐Temperature Adaptability in Aqueous Lithium‐Ion Battery

Advanced Science, EarlyView.
A dilute hybrid electrolyte containing only 10 mol% [EMIM][DEP] simultaneously reorganizes the water hydrogen‐bond network and creates an ionic‐liquid‐rich region at the anode. This coupled bulk and interfacial regulation suppresses freezing and hydrogen evolution, broadens the electrochemical stability window, and enables an aqueous LMO/LTP full cell ...
Jiwei He, Le Zhou, Mengmeng Cong, Keqiao Li, Donggyu Lee, Jiacheng Ji, Jinyu Deng, Zhigang Li, Baoling Huang   +8 more
wiley   +1 more source

Development and Evaluation of the Firefighter Exposure to Carcinogens Scale. [PDF]

J Occup Environ Med
McGrath PJ, Akbari-Fakhrabadi M, Chaplin WF, Saryeddine T, Pawlett G, Laroche E, Petrik J, Irwin I, Caban-Martinez AJ, Hervieux V, Xiong T, McDonald MK, Wang J, Yakovenko I.   +13 more
europepmc   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Effects of adding unstable-surface balance training to resistance training on balance and agility performance in male college ballet dancers. [PDF]

Front Physiol
Yang L, Zhen N, Li M.
europepmc   +1 more source

Social Mobility, Self-Selection, and the Persistence of Class Inequality in Electoral Participation. [PDF]

Br J Sociol
Melli G, de Graaf ND, Evans G.
europepmc   +1 more source

Exploring the influence of electoral political orientation on health outcomes: a scoping review. [PDF]

Cad Saude Publica
Mejía JFR, Boing AF, Peres MA.
europepmc   +1 more source