Results 171 to 180 of about 267 (225)

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

An objective Bayesian method for including parameter uncertainty in ensemble model output statistics

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Conventional model output statistics and ensemble model output statistics methods for calibrating ensemble forecasts lead to severe underestimation of the probabilities of ensemble extremes (in blue). This is because they ignore statistical parameter uncertainty.
Stephen Jewson, Leonardo Olivetti, Gabriele Messori, Paul J. Northrop, Trevor Sweeting   +4 more
wiley   +1 more source

Simulating the year to minute wind spectrum with mesoscale‐coupled large‐eddy simulations

Quarterly Journal of the Royal Meteorological Society, EarlyView.
We coupled a large‐eddy simulation (resolution 50 m) to a mesoscale model (resolution 2 km), which takes boundary conditions from the ERA5 reanalysis. When using a large enough mesoscale domain (𝒪(1000 km)), the simulation setup can reproduce the observed temporal wind spectrum reasonably at all scales between one year and one minute. Furthermore, such
Bernard Postema, Chiel C. van Heerwaarden, Bart J.H. van Stratum, Pim van Dorp, Peter Baas, Harm J.J. Jonker   +5 more
wiley   +1 more source

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

Responsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin, Yujing Li, Guanghao Wu, Yubing Guo   +3 more
wiley   +1 more source

Beyond Compliance: Corporate Governance and the Paradox of Gender Equality: Evidence From EU Firms

Sustainable Development, EarlyView.
ABSTRACT The UN Sustainable Development Goal (SDG) 5 on gender equality is central to the European Union's sustainability and corporate governance agenda. While recent EU regulations have intensified expectations around board gender diversity (BGD) and social disclosure, the organisational drivers through which governance quality translates into ...
Suzan Dsouza, Radhika Lakshminarayanan, Suzana Košir   +2 more
wiley   +1 more source

Probing the Energy Trilemma Pillars: Do Innovation Pathways Deliver Cleaner and More Equitable Energy Systems?

Sustainable Development, EarlyView.
ABSTRACT Balancing reliable energy supply, equitable access, and environmental sustainability is a central challenge of the global energy transition. This study examines how innovation influences the energy trilemma by shaping energy security, energy equity, and environmental sustainability across 115 countries from 2011 to 2023.
Kingsley Imandojemu, Omozele Lynda Showunmi, Felix Orole, Damilola Felix Eluyela, Hammed Oluwaseyi Musibau, Romanus Osabohien   +5 more
wiley   +1 more source

A Comparative Evaluation of Carbonaceous and Alloy Type Anodes for Sodium‐Ion Batteries: Capacity, Scalability, and Sustainability Perspectives

Small, EarlyView.
This review critically compares the electrochemical performance of carbon‐based and alloy‐type anodes for sodium‐ion batteries, with an emphasis on strategies that enhance practical deployment. It highlights how synergistic optimization of microstructure, electrolyte, and presodiation improves hard carbon, while nanostructuring and interfacial ...
Anele Tshaka, Usisipho Feleni, Moshawe J. Madito, Mesfin Abayneh Kebede   +3 more
wiley   +1 more source

Development of switching and adjustment devices for switch rails and proposal of a point of turnout to reduce maintenance labour

Transactions of the JSME (in Japanese)
Shingo TAMAGAWA, Masashi UEDA, Shintaro YASUDA, Akito HOSOMI   +3 more
openaire   +1 more source

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Selection of shape for turnout curve of high-speed switches

Transport of the Urals, 2020
The main factor at determination of radius of turnout curve under the conditions of comfortable driving is the limitation of centrifugal acceleration increment amount per unit time. For this reason, at designing high-speed switches it is advisable to use variable-radius curves as a turnout curve.
Alexey Alexeevich Loktev, Vadim Vadimovich Korolev, Irina Viktorovna Shishkina, Vladislav Sergeevich Kuskov   +3 more
openaire   +1 more source

FAULT DIAGNOSIS OF TURNOUT SWITCH MACHINE BASED ON BRAIN-INSPIRED INTELLIGENCE

3rd International Workshop on Structural Health Monitoring for Railway System (IWSHM-RS 2021), 2021
As the core equipment to control the running direction of railway vehicle, the turnout switch machine, its failure will lead to a series of problems. At present, more and more researchers conduct intelligent re-search on its fault diagnosis. In this paper, aiming at different types of faults during the operation of turnout switch machines, a spiking ...
CAO YUAN, ZHOU YUHAN, SUN YONGKUI
openaire   +1 more source