The Impact of Complement Factor H-Related Protein Gene Deletions on Kidney Transplantation. [PDF]
In this study, we found that rs7542235 allele G tags a deletion of the CFHR1 gene. We also found that rs6677604 allele A tags a deletion of the whole CFHR3–1 locus. The plasma proteomics studies show that both variants are associated with an altered expression of FH/FHR proteins thus revealing a novel level of intricate regulation of the complement ...
Markkinen S +6 more
europepmc +2 more sources
Long-term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores. [PDF]
FinnGen data of 213 942 women was utilized in order to investigate the risk of cardiovascular disease in women with and without hypertensive disorders of pregnancy and with diverse genetic risks for cardiovascular disease and preeclampsia measured with polygenic risk scores.
Kivioja A +8 more
europepmc +2 more sources
Koulutusyhteistyön kohtalonvuodet [PDF]
Matkailualan tutkimus- ja koulutusinstituutissa (MTI) on kolmen eri koulutusasteen – toisen asteen, ammattikorkeakoulun ja yliopiston – koulutusyhteistyön kehittäminen toiminnan keskiössä.
Vehkaperä, Mikko
core +2 more sources
Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki +10 more
wiley +1 more source
Kuntoutujien näkökulma työeläkekuntoutuksen suunnitteluun : Työkokeiluun osallistuvien kuntoutujien haastatteluihin perustuva tutkimus [PDF]
Tutkimuksessa tarkastellaan kuntoutujien kokemuksia ja näkemyksiä työeläkekuntoutukseen hakeutumisesta ja kuntoutuksen suunnittelusta. Tutkimus perustuu vuonna 2023 työkokeiluun osallistuneiden kuntoutujien haastatteluihin ja on ensimmäinen osa laajempaa
Liukko, Jyri +2 more
core
ABSTRACT Automation in public administration is often seen as a recent, purely digital phenomenon that transforms decision‐making and governance. This article challenges that view by elucidating a historical continuum in the automation of administrative decision‐making.
Aleksander Heikkinen +2 more
wiley +1 more source
Holding out on restructuring negotiations: A legal analysis over Finnish and Swedish legislation
Abstract This article examines how Finnish and Swedish restructuring laws create opportunities for creditors to hold out on restructuring negotiations. Using Anthony Casey's new bargaining theory and the traditional creditors' bargain model as analytical frames, the study argues that holdouts arise when ex ante rights – particularly security interests,
Anssi Kärki
wiley +1 more source
Summary Selenium is an essential trace element involved in numerous physiological processes, including antioxidant defence, regulation of thyroid hormone metabolism, immune function, and reproductive health. The aim of this scientific opinion was to assess dietary selenium intake in the adult population of the Republic of Croatia and to evaluate ...
Ivona Sučić +6 more
wiley +1 more source
Identification Environment, School Identification and School Burnout: Multilevel Models
ABSTRACT Most research on well‐being in social psychology has focused on individuals. Based on the social identity approach to health, we examined how the average strength of social identification within a group—a measure of the ‘identification environment’—affects group members’ burnout symptoms and moderates the association between their social ...
Eerika Finell +4 more
wiley +1 more source
Oulun seudun ammattikorkeakoulun tutkimus-, kehitys- ja innovaatiotyön käsitteet ja toimijat [PDF]
Ammattikorkeakoulun tutkimus- ja kehitystyötä toteutetaan tiiviissä yhteistyössä yritysten ja työelämän kanssa. Sen avulla tuotetaan alueen tarpeisiin osaamista sekä edistetään elinkeinoelämän, yhteiskunnan ja hyvinvoinnin myönteistä kehitystä ...
Koivunen, Kirsi +2 more
core

