Results 51 to 60 of about 49,483 (262)
Advanced Science, EarlyView.ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun +10 more
wiley +1 more source
TV Series, 2018 This paper explores the hidden consequences of a simple observation: Westworld uses the time-proven recipes of conspiracy narrative to create a mystery transmedia universe, the secrets of which viewers are incited to elucidate. The consequences of such a
Sébastien Lefait
doaj +1 more source
Advanced Science, EarlyView.An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan +10 more
wiley +1 more source
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
TV Series, 2015 This article aims at reviewing the evolution of U.S. political dramas over the last fifteen years through a compared analysis of two similar scenes from The West Wing (NBC, 1999-2006) and House of Cards (Netflix, 2013-), in which the main character ...
Marjolaine Boutet
doaj +1 more source
Advanced Science, EarlyView.Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu +9 more
wiley +1 more source
From Oz to Lockup: Bringing Prison Life (Back) Home
TV Series, 2012 This paper examines HBO’s prison drama Oz. I connect the 1990s depictions of prison life in Oz to the more recent prevalence of prison shows like Lockup, currently shown weekly on MSNBC. While the two series belong to different genres (fictional drama vs.
Claudia Schippert
doaj +1 more source
Advanced Science, EarlyView.Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou +16 more
wiley +1 more source
Structured prediction for speaker identification in TV series [PDF]
Interspeech 2015, 2015 Though radio and TV broadcast are highly structured documents, state-of-the-art speaker identification algorithms do not take advantage of this information to improve prediction performance: speech turns are usually identified independently from each other, using unstructured multi-class classification approaches.
Knyazeva, Elena +3 more
openaire +2 more sources
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Advanced Science, EarlyView.Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source