Results 101 to 110 of about 18,123 (142)

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models. [PDF]

Oncotarget, 2018
Vena F, Jia R, Esfandiari A, Garcia-Gomez JJ, Rodriguez-Justo M, Ma J, Syed S, Crowley L, Elenbaas B, Goodstal S, Hartley JA, Hochhauser D.   +11 more
europepmc   +1 more source

Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. [PDF]

Nat Commun, 2019
Montero J, Gstalder C, Kim DJ, Sadowicz D, Miles W, Manos M, Cidado JR, Paul Secrist J, Tron AE, Flaherty K, Stephen Hodi F, Yoon CH, Letai A, Fisher DE, Haq R.   +14 more
europepmc   +1 more source

The multi-strategy hybrid forecasting base on SSA-VMD-WST for complex system. [PDF]

PLoS One
Su H, Ma S, Xu X.
europepmc   +1 more source

DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance. [PDF]

J Clin Invest, 2019
Togami K, Pastika T, Stephansky J, Ghandi M, Christie AL, Jones KL, Johnson CA, Lindsay RW, Brooks CL, Letai A, Craig JW, Pozdnyakova O, Weinstock DM, Montero J, Aster JC, Johannessen CM, Lane AA.   +16 more
europepmc   +1 more source

A hybrid framework: singular value decomposition and kernel ridge regression optimized using mathematical-based fine-tuning for enhancing river water level forecasting. [PDF]

Sci Rep
Ahmadianfar I, Farooque AA, Ali M, Jamei M, Jamei M, Yaseen ZM.   +5 more
europepmc   +1 more source

A Novel α_IIbβ₃ Antagonist from Snake Venom Prevents Thrombosis without Causing Bleeding. [PDF]

Toxins (Basel), 2019
Kuo YJ, Chung CH, Pan TY, Chuang WJ, Huang TF.   +4 more
europepmc   +1 more source

Leveraging SHapley Additive exPlanations (SHAP) and fuzzy logic for efficient rainfall forecasts. [PDF]

Sci Rep
Malakouti SM.
europepmc   +1 more source

Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer. [PDF]

Cancer Discov, 2016
Le X, Antony R, Razavi P, Treacy DJ, Luo F, Ghandi M, Castel P, Scaltriti M, Baselga J, Garraway LA.   +9 more
europepmc   +1 more source

Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. [PDF]

Int J Mol Sci, 2017
Murphy RA, Stafford RM, Petrasovits BA, Boone MA, Valentovic MA.   +4 more
europepmc   +1 more source

Toward Active Distributed Fiber-Optic Sensing: A Review of Distributed Fiber-Optic Photoacoustic Non-Destructive Testing Technology. [PDF]

Sensors (Basel)
Wu Y, Fu X, Li J, Gui X, Qiu J, Li Z.
europepmc   +1 more source