Results 21 to 30 of about 18,123 (142)
Translational pharmacokinetic-pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose. [PDF]
Abstract Tepotinib is a highly selective and potent MET inhibitor in development for the treatment of patients with solid tumors. Given the favorable tolerability and safety profiles up to the maximum tested dose in the first‐in‐human (FIH) trial, an efficacy‐driven translational modeling approach was proposed to establish the recommended phase II dose
Xiong W +8 more
europepmc +2 more sources
The large-scale integration of coordinated offshore wind and offshore photovoltaic (PV) generation introduces pronounced power fluctuations due to the intrinsic randomness and intermittency of renewable energy sources (RESs). These fluctuations pose significant challenges to the secure, stable, and economical operation of modern power systems.
Chenghuan Tian +5 more
openaire +2 more sources
EMD-based filtering (EMDF) of low-frequency noise for speech enhancement [PDF]
An Empirical Mode Decomposition based filtering (EMDF) approach is presented as a post-processing stage for speech enhancement. This method is particularly effective in low frequency noise environments.
Navin Chatlani +4 more
core +4 more sources
Performance Evaluation of Blind Modal Identification in Large-Scale Civil Infrastructure
The monitoring and maintenance of existing civil infrastructure has recently received worldwide attention. Several structural health monitoring methods have been developed, including time-, frequency-, and time–frequency domain methods of modal ...
Ali Abasi, Ayan Sadhu
doaj +1 more source
Evapotranspiration is one of agricultural water management's most significant and impactful hydrologic processes. A new multi-decomposition deep learning-based technique is proposed in this study to forecast weekly reference evapotranspiration (ETo) in ...
Masoud Karbasi +6 more
doaj +1 more source
Force constant potentials provided via the hiphive package are combined with GPU‐accelerated molecular dynamics simulations via the GPUMD package to obtain an accurate, transferable, and highly efficient approach for sampling the dynamic properties of materials in general and the lattice thermal conductivity in particular.
Joakim Brorsson +8 more
wiley +1 more source
Multivariable passive method for detection of islanding events in renewable energy based power grids
Abstract Penetration of distributed generation resources (DGR) in power grid is rapidly increasing to meet future energy demand efficiently. It helps in mitigating the problems of high carbon emission, green house effect, and increased cost of oil and natural gases.
Nagendra Kumar Swarnkar +3 more
wiley +1 more source
Noise source identification is the first key step to reduce the noise pressure level of the carpet tufting machine. For identifying the main noise sources of the carpet tufting machine, the single channel blind source separation (SCBSS) method is proposed to separate the acquired single channel noise, and the time‐frequency signal analysis is applied ...
Xiaowei Sheng +4 more
wiley +1 more source
Strong nonstationary and nonlinearity are the main characteristics in the short‐term traffic flow data, which frustrates traditional methods (e.g., autoregressive integrated moving average and deep belief network) to provide a satisfactory prediction.
LeiNa Zhao +4 more
wiley +1 more source
Feature Extraction Method for Hidden Information in Audio Streams Based on HM‐EMD
Using fake audio to spoof the audio devices in the Internet of Things has become an important problem in modern network security. Aiming at the problem of lack of robust features in fake audio detection, an audio streams’ hidden feature extraction method based on a heuristic mask for empirical mode decomposition (HM‐EMD) is proposed in this paper ...
Jiu Lou +4 more
wiley +1 more source

