Results 111 to 120 of about 1,081,563 (177)
A Domain Extender for the Ideal Cipher [PDF]
, 2010 peer reviewedWe describe the first domain extender for ideal ciphers, i.e. we show a construction that is indifferentiable from a 2n-bit ideal cipher, given a n-bit ideal cipher.
Dodis, Yevgeniy +3 more
core
AI Alignment Versus AI Ethical Treatment: 10 Challenges
Analytic Philosophy, EarlyView.ABSTRACT A morally acceptable course of AI development should avoid two dangers: creating unaligned AI systems that pose a threat to humanity and mistreating AI systems that merit moral consideration in their own right. This paper argues these two dangers interact and that if we create AI systems that merit moral consideration, simultaneously avoiding ...
Adam Bradley, Bradford Saad
wiley +1 more source
Simulations All the Way Up! An Atheist's Response to the Fine‐Tuning Argument
Analytic Philosophy, EarlyView.ABSTRACT So the Fine‐tuning Argument goes, because it is so unlikely for the physical constants of the laws of nature to have taken the values that they in fact take, we should significantly raise our credence that God exists. Simulation Arguments argue that our world might be (or, in stronger versions, that it probably is) a mere computer simulation ...
Nikk Effingham
wiley +1 more source
An Introduction to Rational Constructivism in Cognitive Development
Topics in Cognitive Science, EarlyView.Abstract Rational constructivism is a contemporary theory of cognitive development. It proposes that children generate, tweak, and radically revise theories, beliefs, and representations by integrating evidence with existing knowledge via probabilistic inferential learning mechanisms.
Rebekah A. Gelpi +3 more
wiley +1 more source
Extended Substitution Cipher Chaining mode (ESCC) [PDF]
, 2009 In this paper, we present a new tweakable narrow-block mode of operation, the Extended Substitution Cipher Chaining mode (ESCC), that can be efficiently deployed in disk encryption applications.
Mohamed Abo El-Fotouh, Klaus Diepold
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck +13 more
wiley +1 more source
Quantitative Biology, Volume 14, Issue 4, December 2026.Abstract Manual curation of gene–disease–phenotype relationships from the human genetics literature is a persistent bottleneck for maintaining its bioinformatics databases. Whereas large language models (LLMs) offer a promising alternative, there is currently no systematic benchmark that evaluates whether state‐of‐the‐art commercial LLMs can perform ...
Danqing Yin +6 more
wiley +1 more source
Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic
Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.To enable incorporation of l‐2‐aminodecanoic acid into polymyxin by fermentation, a single Trp‐to‐Ala substitution is rationally introduced into the adenylation‐domain residue of its nonribosomal peptide synthetase (NRPS) and efficiently switches substrate selectivity. The engineered strain produces biologically active Ada‐polymyxin, demonstrating that
Maximilian Müll +7 more
wiley +2 more sources
Dead Ends and Policy Change in Chinese Experimental Governance
Governance, Volume 39, Issue 4, December 2026.ABSTRACT Not all policy change is expansive, yet non‐expansive trajectories remain underexamined. This article introduces the concept of dead ends: a stage of the policy process in which initiatives cease to develop or be implemented in their existing form, structuring subsequent policy change such as rollback, redirection, or termination.
Vincent Brussee
wiley +1 more source