Results 21 to 30 of about 57 (57)
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
ABSTRACT Drawing on social cognitive theory, this study examined the role of growth translation mindset (GTM) in linking AI‐mediated informal digital learning of English (AI‐IDLE) to translation performance among Chinese EFL learners. Quantitative data were collected from 378 college students, followed by 12 semi‐structured interviews.
Jin Liu +5 more
wiley +1 more source
Abstract Research on business ecosystems has illuminated how ecosystems emerge, evolve, and transform, revealing ecosystem‐level dynamics and the central actors that orchestrate them. Yet, it is individual firms that continuously attempt to establish and shift the roles they play within ecosystems through the vision and choices of their strategic ...
Paolo Aversa +3 more
wiley +1 more source
Proposed model of metabolic convergence on the target of rapamycin (TOR) pathway in Cryphonectria parasitica. Twelve core genes involved in diverse metabolic pathways act as upstream regulators or downstream effectors of TOR kinase. Dysregulation of these genes mimics an inhibited TOR state, leading to restricted hyphal growth and enhanced trehalose ...
Yo‐Han Ko +4 more
wiley +1 more source
Engineered surface strategies to manage dental implant‐related infections
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Twelve‐Month Discontinuation of Contraceptive Methods: A Global Systematic Review and Meta‐Analysis
Abstract Monitoring contraceptive discontinuation is crucial to reduce unmet needs and unintended pregnancies while supporting person‐centered counseling. The objective is to summarize discontinuation rates by method type (long‐acting reversible contraceptive [LARC] or short‐acting reversible contraceptive [SARC]), type (abandonment or switching), and ...
Fernanda Gontijo Araújo +3 more
wiley +1 more source
ABSTRACT Background and Purpose Prone positioning for play (‘Tummy Time’) is an evidence‐based recommendation that supports early sensory‐motor development during infancy. Infants who require neonatal intensive care face a heightened risk of motor developmental delays, underscoring the importance of early developmental care practices.
Amruta Chutke +3 more
wiley +1 more source
A nickel‐substituted polyoxometalate catalyst enables efficient lignin degradation into monoaromatic compounds in a methanol–water solution. ABSTRACT The transition from fossil‐based resources to renewable feedstocks is a cornerstone of industrial decarbonization.
Dorothea Voß +4 more
wiley +1 more source
Abstract Since holistic scoring leaves room for multiple solutions and creativity, it seems an efficient and effective way to evaluate student performance. However, in practice, there are different views of what holistic scoring entails, what matching instruments look like, and how they should be designed to reap the benefits and avoid the drawbacks ...
Anne Lohuis +2 more
wiley +1 more source
Abstract Children with neurodevelopmental or mental health diagnoses often face barriers to their successful psychosocial functioning at school. This study aimed to systematically review the key characteristics and quality of primary school‐based interventions that evaluate psychosocial functioning and to conduct a meta‐analysis of the interventions ...
Katherine Spender +5 more
wiley +1 more source

