Results 1 to 10 of about 1,841,942 (222)

What the geological past can tell us about the future of the ocean’s twilight zone [PDF]

Nature Communications, 2023
Paleontological reconstructions of plankton community structure during warm periods of the Cenozoic (last 66 million years) reveal that deep-dwelling ‘twilight zone’ (200–1000 m) plankton were less abundant and diverse, and lived much closer to the ...
Katherine A. Crichton, Jamie D. Wilson, Andy Ridgwell, Flavia Boscolo-Galazzo, Eleanor H. John, Bridget S. Wade, Paul N. Pearson   +6 more
doaj   +3 more sources

Community differences and potential function along the particle size spectrum of microbes in the twilight zone [PDF]

Microbiome
Background The twilight zone, which extends from the base of the euphotic zone to a depth of 1000 m, is the major area of particulate organic carbon (POC) remineralization in the ocean. However, little is known about the microbial community and metabolic
Yue Zhang, Hongbin Liu, Hongmei Jing
doaj   +3 more sources

Metabolic activity and community structure of prokaryotes associated with particles in the twilight zone of the South China Sea [PDF]

Frontiers in Microbiology, 2022
The twilight zone is an important depth of the ocean where particulate organic matter (POM) remineralization takes place, and prokaryotes contribute to more than 70% of the estimated remineralization.
Hao Liu, Fangzhou Wang, Fangzhou Wang, Hongbin Liu, Hongbin Liu, Hongbin Liu, Hongmei Jing, Hongmei Jing, Hongmei Jing   +8 more
doaj   +3 more sources

EnsembleFam: towards more accurate protein family prediction in the twilight zone [PDF]

BMC Bioinformatics, 2022
Background Current protein family modeling methods like profile Hidden Markov Model (pHMM), k-mer based methods, and deep learning-based methods do not provide very accurate protein function prediction for proteins in the twilight zone, due to low ...
Mohammad Neamul Kabir, Limsoon Wong
doaj   +3 more sources

Evolutionary distances in the twilight zone--a rational kernel approach. [PDF]

PLoS ONE, 2010
Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly.
Roland F Schwarz, William Fletcher, Frank Förster, Benjamin Merget, Matthias Wolf, Jörg Schultz, Florian Markowetz   +6 more
doaj   +9 more sources

Embedding-based alignment: combining protein language models with dynamic programming alignment to detect structural similarities in the twilight-zone. [PDF]

Bioinformatics
Motivation Language models are routinely used for text classification and generative tasks. Recently, the same architectures were applied to protein sequences, unlocking powerful new approaches in the bioinformatics field.
Pantolini L, Studer G, Pereira J, Durairaj J, Tauriello G, Schwede T.   +5 more
europepmc   +2 more sources

"Did I get into the twilight zone somehow?": sexual and gender minority cancer caregiver experiences during COVID. [PDF]

Cancer Causes Control, 2023
The COVID-19 pandemic created new challenges for cancer patients and caregivers. Little is known about the confluence of the pandemic and people with multiple marginalized identities, such as those in the Sexual and Gender Minority (SGM) community.
Adler Jaffe S, Jacobson K, Farnbach Pearson AW, Baca LA, Dimauro N, Kano M.   +5 more
europepmc   +2 more sources

Using 228Th/228Ra Disequilibrium to Constrain Particulate Organic Carbon Export From the Upper Twilight Zone of the Northern South China Sea

Geochemistry, Geophysics, Geosystems, 2023
We utilized the 228Th/228Ra and 234Th/238U disequilibrium methods to estimate the export of particulate organic carbon (POC) from the upper twilight zone in the northern South China Sea during four cruises from August 2009 to May 2011, covering an entire
Fangfang Deng, Feng Lin
doaj   +2 more sources

Living in the twilight zone: a qualitative study on the experiences of patients with advanced cancer obtaining long-term response to immunotherapy or targeted therapy. [PDF]

J Cancer Surviv, 2022
The introduction of immunotherapy and targeted therapy has drastically improved the life expectancy of patients with advanced cancer. Despite improved survival, obtaining long-term response can be highly distressing and comes with uncertainties that ...
Zwanenburg LC, Suijkerbuijk KPM, van Dongen SI, Koldenhof JJ, van Roozendaal AS, van der Lee ML, Schellekens MPJ.   +6 more
europepmc   +2 more sources

In the twilight zone of protein sequence homology: do protein language models learn protein structure? [PDF]

Bioinform Adv
Motivation Protein language models based on the transformer architecture are increasingly improving performance on protein prediction tasks, including secondary structure, subcellular localization, and more.
Kabir A, Moldwin A, Bromberg Y, Shehu A.
europepmc   +2 more sources