Results 241 to 250 of about 113,233 (309)

Attention-deficit/hyperactivity disorder (ADHD) in adults: evidence base, uncertainties and controversies. [PDF]

open access: yesWorld Psychiatry
Cortese S   +19 more
europepmc   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

open access: yesAdvanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han   +9 more
wiley   +1 more source

Association of hyperactivity-impulsivity and inattention symptom profiles with suicide attempt: an 18-year population-based cohort study. [PDF]

open access: yesBMJ Ment Health
Spodenkiewicz M   +14 more
europepmc   +1 more source

The power of parenting: mitigating conduct problems among adolescents carrying genetic risk. [PDF]

open access: yesFront Child Adolesc Psychiatry
Choi M   +6 more
europepmc   +1 more source

Polygenic score prediction of psychopathology dimensions and diagnoses within and between families

open access: yes
Lin Y   +7 more
europepmc   +1 more source

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